iPTMnet Report for O60381 (HBP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60381 / HBP1_HUMAN
Protein Name HMG box-containing protein 1
Gene Name Name: HBP1
Organism Homo sapiens (Human)

PRO ID PR:O60381
DAG View
PRO Name HMG box-containing protein 1 (human)
Definition An HMG box-containing protein 1 that is encoded in the genome of human.
Short Label hHBP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60381 (HBP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K16 Ubiquitination PhosphoSitePlus
K23 Ubiquitination PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
S156 O-Glycosylation GlyGen 30059200, 29351928
S156 Phosphorylation PhosphoSitePlus
S157 Phosphorylation PhosphoSitePlus
S158 Phosphorylation PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
K171 Acetylation PhosphoSitePlus
K225 Ubiquitination PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
K263 Ubiquitination PhosphoSitePlus
K297 Acetylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K305 Acetylation PhosphoSitePlus
K305 Ubiquitination PhosphoSitePlus
K307 Acetylation PhosphoSitePlus
S372 Phosphorylation PhosphoSitePlus
R378 Methylation PhosphoSitePlus
S380 Phosphorylation PhosphoSitePlus   RLIMS-P 29355710
S382 Phosphorylation PhosphoSitePlus
K398 Ubiquitination PhosphoSitePlus
S402 Phosphorylation Q15759 (MAPK11) , Q16539 (MAPK14) neXtProt   phospho.ELM   PhosphoSitePlus   Signor 14612426
K416 Ubiquitination PhosphoSitePlus
K419 Acetylation PhosphoSitePlus
K419 Ubiquitination PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus
K433 Ubiquitination PhosphoSitePlus
T453 Phosphorylation PhosphoSitePlus
T484 Phosphorylation PhosphoSitePlus   RLIMS-P 29355710
K488 Ubiquitination PhosphoSitePlus
K495 Ubiquitination PhosphoSitePlus
K503 Ubiquitination PhosphoSitePlus
S509 Phosphorylation PhosphoSitePlus   RLIMS-P 29355710


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S135 C135 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S158 F158 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S159 L159 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K171 E171 Biomuta DOID:1324 / lung cancer [ cosmic ]
K255 R255 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S372 N372 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R378 C378 Biomuta DOID:4159 / skin cancer [ cosmic ]
K495 T495 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K503 N503 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]