iPTMnet Report for O60347 (TBC1D12)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60347 / TBC12_HUMAN
Protein Name TBC1 domain family member 12
Gene Name Name: TBC1D12
Synonyms:KIAA0608;
Organism Homo sapiens (Human)

PRO ID PR:O60347
DAG View
PRO Name TBC1 domain family member 12 (human)
Definition A TBC1 domain family member 12 that is encoded in the genome of human.
Short Label hTBC1D12
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60347 (TBC1D12) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S113 Phosphorylation PhosphoSitePlus
R153 Methylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus
S267 Phosphorylation PhosphoSitePlus
S315 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K335 Methylation PhosphoSitePlus
K345 Methylation PhosphoSitePlus
K430 Acetylation PhosphoSitePlus
K434 Acetylation PhosphoSitePlus
K438 Acetylation PhosphoSitePlus
Y707 Phosphorylation PhosphoSitePlus
S747 Phosphorylation PhosphoSitePlus   UniProt 19690332
T748 Phosphorylation PhosphoSitePlus   UniProt 19690332


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S193 F193 Biomuta DOID:1324 / lung cancer [ cosmic ]
S267 C267 Biomuta DOID:1612 / breast cancer [ cosmic ]
Y707 C707 Biomuta DOID:3571 / liver cancer [ cosmic ]