iPTMnet Report for O60336 (MAPKBP1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60336 / MABP1_HUMAN
Protein Name Mitogen-activated protein kinase-binding protein 1
Gene Name Name: MAPKBP1
Synonyms:JNKBP1,KIAA0596;
Organism Homo sapiens (Human)

PRO ID PR:O60336
DAG View
PRO Name mitogen-activated protein kinase-binding protein 1 (human)
Definition A mitogen-activated protein kinase-binding protein 1 that is encoded in the genome of human.
Short Label hMAPKBP1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60336 (MAPKBP1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378
T9 Phosphorylation PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus
S20 Phosphorylation PhosphoSitePlus
K81 Ubiquitination PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
S488 Phosphorylation PhosphoSitePlus
K600 Ubiquitination PhosphoSitePlus
K655 Methylation PhosphoSitePlus
K655 Ubiquitination PhosphoSitePlus
S761 Phosphorylation PhosphoSitePlus
S809 Phosphorylation PhosphoSitePlus
S819 Phosphorylation PhosphoSitePlus
S825 Phosphorylation PhosphoSitePlus
S827 Phosphorylation PhosphoSitePlus
S865 Phosphorylation PhosphoSitePlus
C925 Methylation IEDB 31844290
S935 Phosphorylation PhosphoSitePlus
T1062 Phosphorylation PhosphoSitePlus
S1188 Phosphorylation PhosphoSitePlus
S1198 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1216 Phosphorylation PhosphoSitePlus
S1261 Phosphorylation PhosphoSitePlus
S1263 Phosphorylation PhosphoSitePlus
S1283 Phosphorylation PhosphoSitePlus
S1286 Phosphorylation PhosphoSitePlus
S1314 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S20 F20 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S819 R819 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S827 F827 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1188 G1188 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S1263 Y1263 Biomuta DOID:363 / uterine cancer [ icgc ]