iPTMnet Report for O60333 (KIF1B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60333 / KIF1B_HUMAN
Protein Name Kinesin-like protein KIF1B
Gene Name Name: KIF1B
Synonyms:KIAA0591,KIAA1448;
Organism Homo sapiens (Human)

PRO ID PR:O60333
DAG View
PRO Name kinesin-like protein KIF1B (human)
Definition A kinesin-like protein KIF1B that is encoded in the genome of human.
Short Label hKIF1B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60333 (KIF1B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22814378
K7 Acetylation PhosphoSitePlus
R11 Methylation PhosphoSitePlus
C66 Methylation IEDB 31844290
K243 Ubiquitination PhosphoSitePlus
S252 Phosphorylation PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
T276 Phosphorylation PhosphoSitePlus
T277 Phosphorylation PhosphoSitePlus
T301 Phosphorylation PhosphoSitePlus
K355 Ubiquitination PhosphoSitePlus
T467 Phosphorylation PhosphoSitePlus
T522 Phosphorylation PhosphoSitePlus
S527 Phosphorylation PhosphoSitePlus
K552 Ubiquitination PhosphoSitePlus
S572 Phosphorylation PhosphoSitePlus
C581 Methylation IEDB 31844290
C600 S-Nitrosylation dbSNO 26338901
K646 Ubiquitination PhosphoSitePlus
T647 Phosphorylation PhosphoSitePlus
S654 Phosphorylation PhosphoSitePlus
Q663 Phosphorylation UniProt 21406692
E665 Phosphorylation UniProt 21406692, 24275569
K693 Ubiquitination PhosphoSitePlus
Y707 Phosphorylation PhosphoSitePlus
S709 Phosphorylation PhosphoSitePlus
K784 Ubiquitination PhosphoSitePlus
S892 Phosphorylation PhosphoSitePlus
S893 Phosphorylation PhosphoSitePlus
K999 Ubiquitination PhosphoSitePlus
S1035 Phosphorylation PhosphoSitePlus
Y1040 Phosphorylation PhosphoSitePlus
S1054 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1057 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 18669648, 23186163, ...20068231
T1075 Phosphorylation PhosphoSitePlus   UniProt 19690332
K1089 Ubiquitination PhosphoSitePlus
C1138 Methylation IEDB 31844290
N1141 Phosphorylation UniProt 20068231
K1156 Ubiquitination PhosphoSitePlus
S1162 Phosphorylation PhosphoSitePlus
S1211 Phosphorylation PhosphoSitePlus
K1228 Ubiquitination PhosphoSitePlus
T1241 Phosphorylation PhosphoSitePlus
C1280 Methylation IEDB 31844290
S1304 O-Glycosylation GlyGen 30379171, 30059200
S1416 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1432 O-Glycosylation GlyGen 30379171, 30059200
S1432 Phosphorylation PhosphoSitePlus
S1435 Phosphorylation PhosphoSitePlus
S1454 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 23186163, 20068231, ...24275569
S1487 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...20068231
K1507 Ubiquitination PhosphoSitePlus
S1573 Phosphorylation PhosphoSitePlus   UniProt 24275569
T1592 Phosphorylation PhosphoSitePlus
S1598 Phosphorylation PhosphoSitePlus
S1603 Phosphorylation PhosphoSitePlus   UniProt 24275569
S1605 Phosphorylation PhosphoSitePlus
S1610 Phosphorylation PhosphoSitePlus   UniProt 20068231
S1613 Phosphorylation PhosphoSitePlus   UniProt 20068231, 24275569
S1620 Phosphorylation PhosphoSitePlus
T1630 Phosphorylation PhosphoSitePlus
S1632 Phosphorylation PhosphoSitePlus
S1641 Phosphorylation PhosphoSitePlus
S1643 Phosphorylation PhosphoSitePlus
S1645 Phosphorylation PhosphoSitePlus
T1650 Phosphorylation PhosphoSitePlus
S1655 Phosphorylation PhosphoSitePlus
S1658 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1659 Phosphorylation PhosphoSitePlus
T1675 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K1720 Acetylation PhosphoSitePlus
T1764 Phosphorylation PhosphoSitePlus
S1812 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S481 Phosphorylation HPRD 20068231
S1011 Phosphorylation HPRD 19413330, 20058876, 19664994, ...15302935, 18669648, 19415658, 20068231
S1370 Phosphorylation HPRD 20068231
Y1383 Phosphorylation HPRD 20068231
S1384 Phosphorylation HPRD 20068231
S1386 Phosphorylation HPRD 20068231
S1389 Phosphorylation HPRD 20068231
S1408 Phosphorylation HPRD 15302935, 19664994, 20068231
S1441 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231
S1564 Phosphorylation HPRD 20068231
S1567 Phosphorylation HPRD 19664994, 20068231
S1612 Phosphorylation HPRD 18669648
T1629 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
T276 Phosphorylation PhosphoSitePlus
S481 Phosphorylation HPRD 20068231
S663 Phosphorylation HPRD   PhosphoSitePlus 19651622
S665 Phosphorylation HPRD   PhosphoSitePlus 19651622
S669 Phosphorylation PhosphoSitePlus
S724 Phosphorylation PhosphoSitePlus
K728 Ubiquitination PhosphoSitePlus
S733 Phosphorylation PhosphoSitePlus
K825 Ubiquitination PhosphoSitePlus
S863 Phosphorylation PhosphoSitePlus
S868 Phosphorylation PhosphoSitePlus
R915 Methylation PhosphoSitePlus
R916 Methylation PhosphoSitePlus
R918 Methylation PhosphoSitePlus
K930 Methylation PhosphoSitePlus
K930 Ubiquitination PhosphoSitePlus
K939 Ubiquitination PhosphoSitePlus
S971 Phosphorylation PhosphoSitePlus
S1051 Phosphorylation PhosphoSitePlus
S1053 Phosphorylation PhosphoSitePlus
S1069 Phosphorylation PhosphoSitePlus
S1099 Phosphorylation PhosphoSitePlus
Y1100 Phosphorylation PhosphoSitePlus
T1121 Phosphorylation PhosphoSitePlus
T1132 Phosphorylation PhosphoSitePlus
S1141 Phosphorylation HPRD   PhosphoSitePlus 19651622, 20068231
K1146 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 L2 Biomuta DOID:4159 / skin cancer [ cosmic ]
S274 F274 Biomuta DOID:1612 / breast cancer [ cosmic ]
S481 L481 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S527 L527 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K552 N552 Biomuta DOID:363 / uterine cancer [ icgc ]
S663 F663 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
E665 K665 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K728 * Biomuta DOID:3571 / liver cancer [ cosmic ]
S733 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S892 I892 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ]
R915 K915 Biomuta DOID:1612 / breast cancer [ cosmic ]
R916 C916 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R918 H918 Biomuta DOID:10283 / prostate cancer [ cosmic ]
R918 C918 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R918 S918 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S971 C971 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
S971 F971 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1035 Y1035 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y1040 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S1051 N1051 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1141 L1141 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S1304 T1304 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S1370 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S1389 L1389 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1416 * Biomuta DOID:4159 / skin cancer [ cosmic ]
S1435 L1435 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K1507 T1507 Biomuta DOID:363 / uterine cancer [ icgc ]
S1564 F1564 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S1610 F1610 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S1641 C1641 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S1655 F1655 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1659 I1659 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S1812 R1812 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]