iPTMnet Report for O60318 (MCM3AP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60318 / GANP_HUMAN
Protein Name Germinal-center associated nuclear protein
Gene Name Name: MCM3AP
Synonyms:GANP,KIAA0572,MAP80;
Organism Homo sapiens (Human)

PRO ID PR:O60318
DAG View
PRO Name germinal-center associated nuclear protein (human)
Definition A germinal-center associated nuclear protein that is encoded in the genome of human.
Short Label hMCM3AP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60318 (MCM3AP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S46 Phosphorylation PhosphoSitePlus
T96 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30379171, 29351928, 34019948, 35254053, 35132862, 35083852, 35289036, 30620550
S100 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30379171, 29351928, 34019948, 35254053, 35132862, 35083852, 35289036, 30620550
S114 O-Glycosylation GlyGen 34846842
T116 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30379171, 29351928, 34019948, 35254053, 35132862, 35083852, 35289036, 30620550
S117 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30379171, 29351928, 32938750, 34019948, 35254053, 35132862, 35083852, 35289036, 30620550
S123 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30379171, 29351928, 34019948, 35254053, 35132862, 35083852, 35289036, 30620550
T124 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30379171, 29351928, 34019948, 35254053, 35132862, 35083852, 35289036, 30620550
S125 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30379171, 29351928, 34019948, 35254053, 35132862, 35083852, 35289036, 30620550
S137 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30379171, 29351928, 34019948, 35254053, 35132862, 35083852, 35289036, 30620550
K147 Ubiquitination PhosphoSitePlus
S162 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30379171, 29351928, 34019948, 35254053, 35132862, 35083852, 35289036, 30620550
T167 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30379171, 29351928, 34019948, 35254053, 35132862, 35083852, 35289036, 30620550
S173 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30379171, 29351928, 34019948, 35254053, 35132862, 35083852, 35289036, 30620550
S300 Phosphorylation PhosphoSitePlus
T336 Phosphorylation PhosphoSitePlus
K347 Methylation PhosphoSitePlus
S408 Phosphorylation PhosphoSitePlus
T412 Phosphorylation PhosphoSitePlus
S417 Phosphorylation PhosphoSitePlus
S422 Phosphorylation PhosphoSitePlus
S425 Phosphorylation PhosphoSitePlus
S430 Phosphorylation PhosphoSitePlus   UniProt 23186163
K440 Ubiquitination PhosphoSitePlus
R449 Methylation PhosphoSitePlus
K458 Ubiquitination PhosphoSitePlus
S508 Phosphorylation PhosphoSitePlus
S527 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S529 Phosphorylation PhosphoSitePlus
T530 Phosphorylation PhosphoSitePlus
S538 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...20068231
S556 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30379171, 29351928, 34019948, 35254053, 35132862, 35083852, 35289036, 30620550
S557 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
S574 Phosphorylation PhosphoSitePlus
K644 Ubiquitination PhosphoSitePlus
K674 Ubiquitination PhosphoSitePlus
K781 Ubiquitination PhosphoSitePlus
K787 Acetylation PhosphoSitePlus
K787 Ubiquitination PhosphoSitePlus
S814 O-Glycosylation GlyGen 23301498, 33214551, 35138101, ...30379171, 29351928, 34019948, 35254053, 35132862, 35083852, 35289036, 30620550
Y864 Phosphorylation PhosphoSitePlus
Y873 Phosphorylation PhosphoSitePlus
K947 Ubiquitination PhosphoSitePlus
T955 Phosphorylation PhosphoSitePlus
S1101 Phosphorylation PhosphoSitePlus
Y1106 Phosphorylation PhosphoSitePlus
S1139 Phosphorylation PhosphoSitePlus
K1140 Ubiquitination PhosphoSitePlus
K1194 Ubiquitination PhosphoSitePlus
K1241 Acetylation PhosphoSitePlus
C1285 Methylation IEDB 31844290
K1386 Ubiquitination PhosphoSitePlus
K1448 Ubiquitination PhosphoSitePlus
K1512 Ubiquitination PhosphoSitePlus
K1527 Ubiquitination PhosphoSitePlus
K1785 Ubiquitination PhosphoSitePlus
K1801 Ubiquitination PhosphoSitePlus
K1813 Acetylation PhosphoSitePlus
S1836 Phosphorylation PhosphoSitePlus
S1847 Phosphorylation PhosphoSitePlus
T1848 Phosphorylation PhosphoSitePlus
K1873 Ubiquitination PhosphoSitePlus
S1922 Phosphorylation PhosphoSitePlus
T1924 Phosphorylation PhosphoSitePlus
T1925 Phosphorylation PhosphoSitePlus
S1926 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S286 Phosphorylation HPRD 20068231
S430 Phosphorylation HPRD 19413330
S508 Phosphorylation HPRD 20068231
S527 Phosphorylation HPRD 18669648, 20068231, 18707149
S529 Phosphorylation HPRD 20068231
S538 Phosphorylation HPRD 18669648, 20068231
S557 Phosphorylation HPRD 19413330


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S46 F46 Biomuta DOID:5158 / pleural cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
S300 F300 Biomuta DOID:4159 / skin cancer [ cosmic ]
S408 P408 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S422 I422 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S422 N422 Biomuta DOID:4159 / skin cancer [ cosmic ]
R449 S449 Biomuta DOID:1324 / lung cancer [ cosmic ]
K458 N458 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S508 G508 Biomuta DOID:184 / bone cancer [ cosmic ]
S527 G527 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S556 N556 Biomuta DOID:1540 / parathyroid carcinoma [ cosmic ]
K674 E674 Biomuta DOID:3571 / liver cancer [ cosmic ]
K674 R674 Biomuta DOID:3571 / liver cancer [ cosmic ]
K1194 N1194 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K1241 E1241 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K1512 R1512 Biomuta DOID:184 / bone cancer [ cosmic ]
S1836 G1836 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1922 F1922 Biomuta DOID:1612 / breast cancer [ cosmic ]
T1924 A1924 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]