iPTMnet Report for O60306 (AQR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60306 / AQR_HUMAN
Protein Name RNA helicase aquarius
Gene Name Name: AQR
Synonyms:KIAA0560;
Organism Homo sapiens (Human)

PRO ID PR:O60306
DAG View
PRO Name RNA helicase aquarius (human)
Definition An RNA helicase aquarius that is encoded in the genome of human.
Short Label hAQR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60306 (AQR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T14 Phosphorylation PhosphoSitePlus
S16 Phosphorylation PhosphoSitePlus
K44 Ubiquitination PhosphoSitePlus
Y50 Phosphorylation PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
K195 Acetylation PhosphoSitePlus
S235 O-Glycosylation GlyGen 23301498, 34019948, 29351928
T243 O-Glycosylation GlyGen 23301498, 34019948, 29351928
T243 Phosphorylation HPRD   PhosphoSitePlus 20068231
K246 Ubiquitination PhosphoSitePlus
C250 Methylation IEDB 31844290
Y284 Phosphorylation PhosphoSitePlus
S286 Phosphorylation PhosphoSitePlus
S416 Phosphorylation PhosphoSitePlus
K493 Ubiquitination PhosphoSitePlus
Y499 Phosphorylation PhosphoSitePlus
K576 Acetylation PhosphoSitePlus
K604 Ubiquitination PhosphoSitePlus
S622 Phosphorylation PhosphoSitePlus
K667 Ubiquitination PhosphoSitePlus
T672 Phosphorylation HPRD   PhosphoSitePlus 20068231
T771 Phosphorylation PhosphoSitePlus
K775 Ubiquitination PhosphoSitePlus
T776 Phosphorylation PhosphoSitePlus
Y841 Phosphorylation PhosphoSitePlus
K890 Ubiquitination PhosphoSitePlus
Y934 Phosphorylation PhosphoSitePlus
S942 Phosphorylation PhosphoSitePlus
K1045 Acetylation PhosphoSitePlus
K1051 Acetylation PhosphoSitePlus   UniProt 19608861
K1111 Ubiquitination PhosphoSitePlus
S1225 Phosphorylation IEDB 32387766
K1256 Ubiquitination PhosphoSitePlus
S1420 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S16 P16 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K44 N44 Biomuta DOID:1612 / breast cancer [ cosmic ]
Y50 H50 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
S286 F286 Biomuta DOID:4159 / skin cancer [ cosmic ]
T771 I771 Biomuta DOID:4606 / bile duct cancer [ cosmic ]