iPTMnet Report for O60299 (LZTS3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60299 / LZTS3_HUMAN
Protein Name Leucine zipper putative tumor suppressor 3
Gene Name Name: LZTS3
Synonyms:KIAA0552;
Organism Homo sapiens (Human)

PRO ID PR:O60299
DAG View
PRO Name leucine zipper putative tumor suppressor 3 (human)
Definition A leucine zipper putative tumor suppressor 3 that is encoded in the genome of human.
Short Label hLZTS3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60299 (LZTS3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T6 Phosphorylation PhosphoSitePlus
S64 Phosphorylation PhosphoSitePlus
S88 Phosphorylation PhosphoSitePlus
S174 Phosphorylation PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
Y270 Phosphorylation PhosphoSitePlus
T275 Phosphorylation PhosphoSitePlus
S278 Phosphorylation PhosphoSitePlus
S287 Phosphorylation PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
K401 Acetylation PhosphoSitePlus
S497 Phosphorylation PhosphoSitePlus
S622 O-Glycosylation GlyGen 30379171
T648 Phosphorylation PhosphoSitePlus
T661 Phosphorylation PhosphoSitePlus
S670 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T6 M6 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S64 I64 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S88 L88 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S174 F174 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S212 N212 Biomuta DOID:1319 / brain cancer [ cosmic ]
T648 M648 Biomuta [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]