iPTMnet Report for O60296 (TRAK2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60296 / TRAK2_HUMAN
Protein Name Trafficking kinesin-binding protein 2
Gene Name Name: TRAK2
Synonyms:ALS2CR3,KIAA0549;
Organism Homo sapiens (Human)

PRO ID PR:O60296
DAG View
PRO Name trafficking kinesin-binding protein 2 (human)
Definition A trafficking kinesin-binding protein 2 that is encoded in the genome of human.
Short Label hTRAK2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60296 (TRAK2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S84 Phosphorylation PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
C191 Methylation IEDB 31844290
K254 Ubiquitination PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
Y280 Phosphorylation PhosphoSitePlus
S285 Phosphorylation PhosphoSitePlus
S289 Phosphorylation PhosphoSitePlus
K299 Acetylation PhosphoSitePlus
K299 Ubiquitination PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
K385 Ubiquitination PhosphoSitePlus
S387 Phosphorylation PhosphoSitePlus
K396 Ubiquitination PhosphoSitePlus
S420 Phosphorylation PhosphoSitePlus   UniProt 23186163
S430 Phosphorylation PhosphoSitePlus
S498 Phosphorylation PhosphoSitePlus
K510 Ubiquitination PhosphoSitePlus
S567 Phosphorylation PhosphoSitePlus
T639 O-Glycosylation GlyGen 34019948, 35289036
T647 O-Glycosylation GlyGen 34019948, 32938750, 35289036
S648 O-Glycosylation GlyGen 32938750
T654 O-Glycosylation GlyGen 32938750
T657 O-Glycosylation GlyGen 34019948, 35289036
T674 Phosphorylation PhosphoSitePlus
T675 Phosphorylation PhosphoSitePlus
T688 Phosphorylation PhosphoSitePlus
S691 Phosphorylation PhosphoSitePlus
T708 Phosphorylation PhosphoSitePlus
S731 Phosphorylation PhosphoSitePlus
S751 Phosphorylation PhosphoSitePlus
S760 Phosphorylation PhosphoSitePlus
S775 Phosphorylation PhosphoSitePlus
T776 Phosphorylation PhosphoSitePlus
S780 Phosphorylation PhosphoSitePlus
S782 Phosphorylation PhosphoSitePlus
S784 Phosphorylation PhosphoSitePlus
S788 Phosphorylation PhosphoSitePlus
T810 Phosphorylation PhosphoSitePlus
Y816 Phosphorylation PhosphoSitePlus
K831 Methylation PhosphoSitePlus
S889 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y280 Phosphorylation HPRD 18491316
S285 Phosphorylation HPRD 18491316


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K273 N273 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S285 Y285 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S420 L420 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
T688 A688 Biomuta DOID:1319 / brain cancer [ cosmic ]
T688 P688 Biomuta DOID:1612 / breast cancer [ cosmic ]
S731 C731 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S780 * Biomuta DOID:363 / uterine cancer [ cosmic ]