Protein Information

Cytoscape View


UniProt AC / UniProt ID O60292 / SI1L3_HUMAN
Protein Name Signal-induced proliferation-associated 1-like protein 3
Gene Name Name: SIPA1L3
Synonyms:KIAA0545,SPAL3;
Organism Homo sapiens (Human)

PRO ID PR:O60292
DAG View
PRO Name signal-induced proliferation-associated 1-like protein 3 (human)
Definition A signal-induced proliferation-associated 1-like protein 3 that is encoded in the genome of human.
Short Label hSIPA1L3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60292 (SIPA1L3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S17 Phosphorylation PhosphoSitePlus
Y34 Phosphorylation PhosphoSitePlus
S97 Phosphorylation PhosphoSitePlus
S100 Phosphorylation PhosphoSitePlus
S119 Phosphorylation PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus
S135 Phosphorylation PhosphoSitePlus
S142 Phosphorylation PhosphoSitePlus
S146 Phosphorylation HPRD   PhosphoSitePlus 18452278
S158 Phosphorylation PhosphoSitePlus
S170 Phosphorylation PhosphoSitePlus
S171 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S172 Phosphorylation PhosphoSitePlus
T175 Phosphorylation PhosphoSitePlus
T296 Phosphorylation PhosphoSitePlus
S317 Phosphorylation PhosphoSitePlus
T368 Phosphorylation PhosphoSitePlus
S383 Phosphorylation PhosphoSitePlus
T385 Phosphorylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
S401 Phosphorylation PhosphoSitePlus   UniProt 24275569
S451 Phosphorylation PhosphoSitePlus
T469 Phosphorylation PhosphoSitePlus
S487 Phosphorylation PhosphoSitePlus
S493 Phosphorylation PhosphoSitePlus
S782 Phosphorylation PhosphoSitePlus
T785 Phosphorylation PhosphoSitePlus
K799 Ubiquitination PhosphoSitePlus
K812 Ubiquitination PhosphoSitePlus
S960 Phosphorylation PhosphoSitePlus
T1017 Phosphorylation PhosphoSitePlus
T1019 Phosphorylation PhosphoSitePlus
T1063 Phosphorylation PhosphoSitePlus
S1067 Phosphorylation PhosphoSitePlus
T1069 Phosphorylation PhosphoSitePlus
Y1076 Phosphorylation PhosphoSitePlus
S1109 Phosphorylation PhosphoSitePlus
S1111 Phosphorylation PhosphoSitePlus
T1117 Phosphorylation PhosphoSitePlus
S1125 Phosphorylation PhosphoSitePlus
S1130 Phosphorylation PhosphoSitePlus
S1135 Phosphorylation phospho.ELM   PhosphoSitePlus 18220336
T1139 Phosphorylation PhosphoSitePlus
Y1141 Phosphorylation PhosphoSitePlus
T1142 Phosphorylation PhosphoSitePlus
S1144 Phosphorylation PhosphoSitePlus
S1160 Phosphorylation PhosphoSitePlus
S1166 Phosphorylation PhosphoSitePlus
Y1169 Phosphorylation PhosphoSitePlus
S1175 Phosphorylation PhosphoSitePlus
S1233 Phosphorylation PhosphoSitePlus
S1239 Phosphorylation PhosphoSitePlus
S1254 Phosphorylation PhosphoSitePlus
Y1265 Phosphorylation PhosphoSitePlus
S1269 Phosphorylation PhosphoSitePlus
S1270 Phosphorylation PhosphoSitePlus
T1273 Phosphorylation PhosphoSitePlus
S1281 Phosphorylation PhosphoSitePlus
S1283 Phosphorylation PhosphoSitePlus
Y1316 Phosphorylation PhosphoSitePlus
S1364 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 18220336
S1373 Phosphorylation PhosphoSitePlus
Y1376 Phosphorylation PhosphoSitePlus
Y1381 Phosphorylation PhosphoSitePlus
S1382 Phosphorylation PhosphoSitePlus
S1383 Phosphorylation PhosphoSitePlus
S1386 Phosphorylation PhosphoSitePlus
T1387 Phosphorylation PhosphoSitePlus
T1389 Phosphorylation PhosphoSitePlus
Y1416 Phosphorylation PhosphoSitePlus
T1423 Phosphorylation PhosphoSitePlus
S1433 Phosphorylation PhosphoSitePlus
S1440 Phosphorylation PhosphoSitePlus
K1448 Acetylation PhosphoSitePlus   UniProt 19608861
K1448 Methylation PhosphoSitePlus
S1473 Phosphorylation PhosphoSitePlus
K1476 Acetylation PhosphoSitePlus
S1495 Phosphorylation PhosphoSitePlus
S1501 Phosphorylation PhosphoSitePlus
K1507 Methylation PhosphoSitePlus
T1531 Phosphorylation PhosphoSitePlus
S1534 Phosphorylation PhosphoSitePlus
K1537 Ubiquitination PhosphoSitePlus
T1542 Phosphorylation PhosphoSitePlus
S1544 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18669648, 19664994, ...19664995
S1547 Phosphorylation PhosphoSitePlus
S1550 Phosphorylation PhosphoSitePlus
S1559 Phosphorylation PhosphoSitePlus
S1581 Phosphorylation PhosphoSitePlus
S1582 Phosphorylation PhosphoSitePlus
T1583 Phosphorylation PhosphoSitePlus
S1617 Phosphorylation PhosphoSitePlus
S1619 Phosphorylation PhosphoSitePlus
S1622 Phosphorylation PhosphoSitePlus
S1677 Phosphorylation PhosphoSitePlus
S1685 Phosphorylation PhosphoSitePlus
S1692 Phosphorylation PhosphoSitePlus
T1699 Phosphorylation PhosphoSitePlus   UniProt 19690332
T1703 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
T1705 Phosphorylation HPRD   phospho.ELM 18669648
S1707 Phosphorylation PhosphoSitePlus
K1739 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S97 N97 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S317 F317 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T385 M385 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S493 R493 Biomuta DOID:1909 / melanoma [ cosmic ]
T1019 A1019 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T1063 M1063 Biomuta DOID:363 / uterine cancer [ tcga ]
S1067 R1067 Biomuta DOID:363 / uterine cancer [ tcga ]
T1069 I1069 Biomuta DOID:1909 / melanoma [ cosmic ]
S1111 I1111 Biomuta DOID:1115 / sarcoma [ tcga ]
S1125 P1125 Biomuta DOID:263 / kidney cancer [ icgc, tcga ]
S1160 N1160 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S1373 N1373 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S1383 F1383 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
K1448 * Biomuta DOID:1909 / melanoma [ icgc, tcga ]
K1476 R1476 Biomuta DOID:1324 / lung cancer [ tcga ]
T1531 M1531 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
S1544 L1544 Biomuta DOID:1793 / pancreatic cancer [ icgc, tcga ] DOID:10283 / prostate cancer [ cosmic ]
S1559 I1559 Biomuta DOID:1909 / melanoma [ cosmic ]
S1692 G1692 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
T1703 I1703 Biomuta DOID:4362 / cervical cancer [ tcga ]
S1707 T1707 Biomuta DOID:5041 / esophageal cancer [ icgc ]