iPTMnet Report for O60287 (URB1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60287 / NPA1P_HUMAN
Protein Name Nucleolar pre-ribosomal-associated protein 1
Gene Name Name: URB1
Synonyms:C21orf108,KIAA0539,NOP254,NPA1;
Organism Homo sapiens (Human)

PRO ID PR:O60287
DAG View
PRO Name nucleolar pre-ribosomal-associated protein 1 (human)
Definition A nucleolar pre-ribosomal-associated protein 1 that is encoded in the genome of human.
Short Label hURB1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60287 (URB1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K5 Acetylation PhosphoSitePlus
K7 Ubiquitination PhosphoSitePlus
S9 Phosphorylation PhosphoSitePlus
K23 Acetylation PhosphoSitePlus
K23 Ubiquitination PhosphoSitePlus
K27 Sumoylation PhosphoSitePlus
K27 Ubiquitination PhosphoSitePlus
K36 Methylation PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
S54 Phosphorylation PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
K73 Methylation PhosphoSitePlus
K89 Methylation PhosphoSitePlus
T121 Phosphorylation PhosphoSitePlus
Y180 Phosphorylation PhosphoSitePlus
T184 Phosphorylation PhosphoSitePlus
K185 Ubiquitination PhosphoSitePlus
K189 Ubiquitination PhosphoSitePlus
K248 Ubiquitination PhosphoSitePlus
K250 Ubiquitination PhosphoSitePlus
K255 Ubiquitination PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus
C367 Methylation IEDB 31844290
K376 Ubiquitination PhosphoSitePlus
K387 Ubiquitination PhosphoSitePlus
K395 Ubiquitination PhosphoSitePlus
K399 Ubiquitination PhosphoSitePlus
T429 Phosphorylation PhosphoSitePlus
T430 Phosphorylation PhosphoSitePlus
C435 Methylation IEDB 31844290
S457 Phosphorylation IEDB 32387766
K468 Ubiquitination PhosphoSitePlus
T469 O-Glycosylation GlyGen 34931806, 29237092
S517 Phosphorylation PhosphoSitePlus
K585 Ubiquitination PhosphoSitePlus
K616 Ubiquitination PhosphoSitePlus
K621 Ubiquitination PhosphoSitePlus
T706 Phosphorylation IEDB 32387766
S719 Phosphorylation PhosphoSitePlus
Y934 Phosphorylation PhosphoSitePlus
Y1075 Phosphorylation PhosphoSitePlus
T1080 Phosphorylation PhosphoSitePlus
K1085 Ubiquitination PhosphoSitePlus
S1097 Phosphorylation PhosphoSitePlus
K1100 Ubiquitination PhosphoSitePlus
T1101 Phosphorylation PhosphoSitePlus
T1137 Phosphorylation PhosphoSitePlus
T1141 Phosphorylation PhosphoSitePlus
K1142 Ubiquitination PhosphoSitePlus
S1143 Phosphorylation PhosphoSitePlus   UniProt 20068231
K1336 Ubiquitination PhosphoSitePlus
S1347 Phosphorylation PhosphoSitePlus
T1351 Phosphorylation PhosphoSitePlus
S1354 Phosphorylation PhosphoSitePlus
K1356 Ubiquitination PhosphoSitePlus
S1365 Phosphorylation PhosphoSitePlus
S1371 Phosphorylation PhosphoSitePlus
C1386 Methylation IEDB 31844290
K1409 Ubiquitination PhosphoSitePlus
K1432 Ubiquitination PhosphoSitePlus
Y1459 Phosphorylation PhosphoSitePlus
S1460 Phosphorylation PhosphoSitePlus
K1555 Ubiquitination PhosphoSitePlus
K1575 Ubiquitination PhosphoSitePlus
K1627 Ubiquitination PhosphoSitePlus
K1782 Ubiquitination PhosphoSitePlus
K1786 Ubiquitination PhosphoSitePlus
K1799 Ubiquitination PhosphoSitePlus
K1909 Ubiquitination PhosphoSitePlus
K1976 Ubiquitination PhosphoSitePlus
S1986 Phosphorylation PhosphoSitePlus
K1993 Ubiquitination PhosphoSitePlus
K2004 Ubiquitination PhosphoSitePlus
K2012 Ubiquitination PhosphoSitePlus
K2019 Ubiquitination PhosphoSitePlus
K2056 Ubiquitination PhosphoSitePlus
K2141 Ubiquitination PhosphoSitePlus
S2199 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K73 N73 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K185 N185 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
K189 R189 Biomuta DOID:363 / uterine cancer [ cosmic ]
K300 E300 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S457 T457 Biomuta DOID:1324 / lung cancer [ cosmic ]
K468 T468 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1097 A1097 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T1141 M1141 Biomuta DOID:363 / uterine cancer [ icgc ]
S1347 I1347 Biomuta DOID:1324 / lung cancer [ cosmic ]
C1386 Y1386 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
K1575 N1575 Biomuta DOID:363 / uterine cancer [ icgc ]
K1627 R1627 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]