Protein Information

Cytoscape View


UniProt AC / UniProt ID O60282 / KIF5C_HUMAN
Protein Name Kinesin heavy chain isoform 5C
Gene Name Name: KIF5C
Synonyms:KIAA0531,NKHC2;
Organism Homo sapiens (Human)

PRO ID PR:O60282
DAG View
PRO Name kinesin heavy chain isoform 5C (human)
Definition A kinesin heavy chain isoform 5C that is encoded in the genome of human.
Short Label hKIF5C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60282 (KIF5C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K167 Acetylation PhosphoSitePlus
S176 Phosphorylation P53779 (MAPK10) neXtProt   RLIMS-P 19525941, 27013971
K227 Ubiquitination PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus
K253 Ubiquitination PhosphoSitePlus
K274 Ubiquitination PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
T317 Phosphorylation PhosphoSitePlus
T326 Phosphorylation PhosphoSitePlus
K348 Acetylation PhosphoSitePlus
K501 Ubiquitination PhosphoSitePlus
Y590 Phosphorylation PhosphoSitePlus
S596 Phosphorylation PhosphoSitePlus
S610 Phosphorylation PhosphoSitePlus
S615 Phosphorylation PhosphoSitePlus
S660 Phosphorylation PhosphoSitePlus
R692 Methylation PhosphoSitePlus
R711 Methylation PhosphoSitePlus
Y753 Phosphorylation PhosphoSitePlus
K814 Acetylation PhosphoSitePlus
S816 Phosphorylation PhosphoSitePlus
S835 Phosphorylation PhosphoSitePlus
K846 Ubiquitination PhosphoSitePlus
K849 Ubiquitination PhosphoSitePlus
R903 Methylation PhosphoSitePlus
S919 Phosphorylation PhosphoSitePlus
S934 Phosphorylation PhosphoSitePlus   RLIMS-P 27013971
S935 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S316 F316 Biomuta DOID:363 / uterine cancer [ tcga ]
R692 W692 Biomuta DOID:1790 / malignant mesothelioma [ tcga ] DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
S835 F835 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
K849 N849 Biomuta DOID:1612 / breast cancer [ cosmic, icgc, tcga ]
K849 R849 Biomuta DOID:0070003 / blastoma [ cosmic ]
R903 C903 Biomuta DOID:1793 / pancreatic cancer [ icgc ] DOID:1909 / melanoma [ cosmic, tcga ]
S934 * Biomuta DOID:4362 / cervical cancer [ tcga ]