iPTMnet Report for O60269 (GPRIN2)
Protein Information
| UniProt AC / UniProt ID | O60269 / GRIN2_HUMAN |
| Protein Name | G protein-regulated inducer of neurite outgrowth 2 |
| Gene Name | Name: GPRIN2 Synonyms:KIAA0514; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O60269 |
| PRO Name | G protein-regulated inducer of neurite outgrowth 2 (human) |
| Definition | A G protein-regulated inducer of neurite outgrowth 2 that is encoded in the genome of human. |
| Short Label | hGPRIN2 |
| Category | organism-gene |
O60269 (GPRIN2) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S15 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S22 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S24 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S25 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S26 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S27 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R119 | Methylation | score1 | PhosphoSitePlus | |||
| S120 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S122 | Phosphorylation | score1 | PhosphoSitePlus | |||
| R126 | Methylation | score1 | PhosphoSitePlus | |||
| R131 | Methylation | score1 | PhosphoSitePlus | |||
| S140 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S142 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S144 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S266 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S424 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S427 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S429 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S24 | N24 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| S25 | F25 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] | |
| S25 | Y25 | Biomuta | DOID:1319 / brain cancer [ icgc ] | |
| S26 | F26 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| S26 | T26 | Biomuta | DOID:1319 / brain cancer [ cosmic ] | |
| S27 | C27 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S122 | P122 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S122 | A122 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| R126 | H126 | Biomuta | DOID:1612 / breast cancer [ cosmic, icgc ] DOID:11054 / urinary bladder cancer [ icgc ] | |
| R126 | L126 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| R131 | W131 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ] | |
| S429 | F429 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
DAG View