iPTMnet Report for O60264 (SMARCA5)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60264 / SMCA5_HUMAN
Protein Name SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5
Gene Name Name: SMARCA5
Synonyms:SNF2H,WCRF135;
Organism Homo sapiens (Human)

PRO ID PR:O60264
DAG View
PRO Name SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (human)
Definition A SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 that is encoded in the genome of human.
Short Label hSMARCA5
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60264 (SMARCA5) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330
S2 Phosphorylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
S29 Phosphorylation PhosphoSitePlus
S50 Phosphorylation PhosphoSitePlus
S66 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 17081983, 15302935, ...18669648, 24275569, 17693683, 19690332
K71 Ubiquitination PhosphoSitePlus
Y80 Phosphorylation PhosphoSitePlus
K83 Sumoylation PhosphoSitePlus
K83 Ubiquitination PhosphoSitePlus
T113 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 17081983, 20068231, ...16565220
T115 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S116 Phosphorylation IEDB   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 16565220, ...18669648, 27869121
K129 Acetylation PhosphoSitePlus
K132 Acetylation PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
S137 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 18669648, ...14729942, 20068231
Y141 Phosphorylation PhosphoSitePlus
T156 Phosphorylation PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
C165 Methylation IEDB 31844290
S171 Phosphorylation PhosphoSitePlus   UniProt 23186163
K176 Ubiquitination PhosphoSitePlus
K249 Acetylation PhosphoSitePlus
T254 Phosphorylation PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus
C259 Methylation IEDB 31844290
K264 Acetylation PhosphoSitePlus
K264 Ubiquitination PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
K397 Acetylation PhosphoSitePlus
K402 Acetylation PhosphoSitePlus
K418 Ubiquitination PhosphoSitePlus
K430 Acetylation PhosphoSitePlus
K430 Ubiquitination PhosphoSitePlus
S437 Phosphorylation PhosphoSitePlus
K440 Acetylation PhosphoSitePlus   UniProt 19608861
K440 Ubiquitination PhosphoSitePlus
K490 Ubiquitination PhosphoSitePlus
K600 Acetylation PhosphoSitePlus
K600 Ubiquitination PhosphoSitePlus
S629 Phosphorylation PhosphoSitePlus
K644 Ubiquitination PhosphoSitePlus
K647 Acetylation PhosphoSitePlus
K647 Sumoylation PhosphoSitePlus
K647 Ubiquitination PhosphoSitePlus
K665 Ubiquitination PhosphoSitePlus
T670 Phosphorylation PhosphoSitePlus
K683 Acetylation PhosphoSitePlus
K683 Ubiquitination PhosphoSitePlus
T685 Phosphorylation PhosphoSitePlus
K691 Ubiquitination PhosphoSitePlus
K694 Sumoylation PhosphoSitePlus
K694 Ubiquitination PhosphoSitePlus
S698 Phosphorylation PhosphoSitePlus
S699 Phosphorylation PhosphoSitePlus
Y712 Phosphorylation PhosphoSitePlus
Y719 Phosphorylation PhosphoSitePlus
K724 Ubiquitination PhosphoSitePlus
K735 Ubiquitination PhosphoSitePlus
K739 Sumoylation PhosphoSitePlus
K739 Ubiquitination PhosphoSitePlus
Y742 Phosphorylation PhosphoSitePlus
Y747 Phosphorylation PhosphoSitePlus
S755 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16565220
Y798 Phosphorylation PhosphoSitePlus
K799 Ubiquitination PhosphoSitePlus
K814 Ubiquitination PhosphoSitePlus
S825 Phosphorylation PhosphoSitePlus   UniProt 21406692, 20068231
K834 Sumoylation PhosphoSitePlus
K834 Ubiquitination PhosphoSitePlus
K836 Ubiquitination PhosphoSitePlus
K847 Ubiquitination PhosphoSitePlus
K855 Ubiquitination PhosphoSitePlus
T923 Phosphorylation PhosphoSitePlus
K924 Ubiquitination PhosphoSitePlus
K929 Sumoylation PhosphoSitePlus
K929 Ubiquitination PhosphoSitePlus
K945 Acetylation PhosphoSitePlus
K945 Ubiquitination PhosphoSitePlus
Y947 Phosphorylation PhosphoSitePlus
K961 Ubiquitination PhosphoSitePlus
Y970 Phosphorylation PhosphoSitePlus
R974 Methylation PhosphoSitePlus
C976 Methylation IEDB 31844290
K1018 Ubiquitination PhosphoSitePlus
K1036 Acetylation PhosphoSitePlus
R1044 Methylation PhosphoSitePlus
K1049 Acetylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S26 N26 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S116 L116 Biomuta DOID:4159 / skin cancer [ cosmic ]
S116 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
C165 F165 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K176 N176 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S257 Y257 Biomuta DOID:4159 / skin cancer [ cosmic ]
K402 N402 Biomuta DOID:4362 / cervical cancer [ icgc ]
K402 T402 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
Y798 C798 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y798 H798 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
Y798 S798 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K855 N855 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K961 T961 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R974 Q974 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R974 L974 Biomuta DOID:1324 / lung cancer [ cosmic ]
R1044 Q1044 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]