iPTMnet Report for O60256 (PRPSAP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60256 / KPRB_HUMAN
Protein Name Phosphoribosyl pyrophosphate synthase-associated protein 2
Gene Name Name: PRPSAP2
Organism Homo sapiens (Human)

PRO ID PR:O60256
DAG View
PRO Name phosphoribosyl pyrophosphate synthase-associated protein 2 (human)
Definition A phosphoribosyl pyrophosphate synthase-associated protein 2 that is encoded in the genome of human.
Short Label hPRPSAP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60256 (PRPSAP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
T5 Phosphorylation PhosphoSitePlus   UniProt 23186163
S27 Phosphorylation PhosphoSitePlus
K48 Ubiquitination PhosphoSitePlus
Y52 Phosphorylation PhosphoSitePlus
C117 S-Nitrosylation dbSNO 26338901
T144 Phosphorylation PhosphoSitePlus
K188 Acetylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
S189 Phosphorylation PhosphoSitePlus
S192 Phosphorylation PhosphoSitePlus
K194 Acetylation PhosphoSitePlus
S198 Phosphorylation PhosphoSitePlus
S219 Phosphorylation PhosphoSitePlus   UniProt 24275569
S227 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 17081983, 18669648, ...24275569, 19690332, 20068231
S233 Phosphorylation PhosphoSitePlus   UniProt 24275569
S240 Phosphorylation PhosphoSitePlus
K251 Acetylation PhosphoSitePlus
K251 Ubiquitination PhosphoSitePlus
K330 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S219 Phosphorylation HPRD 19413330, 19651622, 20068231
S227 Phosphorylation HPRD 19413330, 17081983, 20230923, ...19651622, 18510355, 18669648, 20166139, 20068231
T338 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T5 M5 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y52 H52 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S192 L192 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S198 Y198 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S219 L219 Biomuta DOID:9256 / colorectal cancer [ cosmic ]