iPTMnet Report for O60241 (ADGRB2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O60241 / AGRB2_HUMAN
Protein Name Adhesion G protein-coupled receptor B2 precursor
Gene Name Name: ADGRB2
Synonyms:BAI2;
Organism Homo sapiens (Human)

PRO ID PR:O60241
DAG View
PRO Name adhesion G protein-coupled receptor B2 (human)
Definition An adhesion G protein-coupled receptor B2 that is encoded in the genome of human.
Short Label hADGRB2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O60241 (ADGRB2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T4 Phosphorylation PhosphoSitePlus
S266 O-Glycosylation GlyGen   UniProt 25326458
Y279 Phosphorylation PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus
T455 Phosphorylation PhosphoSitePlus
T457 Phosphorylation PhosphoSitePlus
T543 Phosphorylation PhosphoSitePlus
Y554 Phosphorylation PhosphoSitePlus
K556 Ubiquitination PhosphoSitePlus
Y594 Phosphorylation PhosphoSitePlus
Y596 Phosphorylation PhosphoSitePlus
Y655 Phosphorylation PhosphoSitePlus
T843 Phosphorylation PhosphoSitePlus
T845 Phosphorylation PhosphoSitePlus
T850 Phosphorylation PhosphoSitePlus
C874 Methylation IEDB 31844290
T1176 Phosphorylation PhosphoSitePlus
Y1351 Phosphorylation PhosphoSitePlus
R1375 Methylation PhosphoSitePlus
R1383 Methylation PhosphoSitePlus
R1384 Methylation PhosphoSitePlus
T1392 Phosphorylation PhosphoSitePlus
T1444 Phosphorylation PhosphoSitePlus
S1511 Phosphorylation PhosphoSitePlus
S1543 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S266 L266 Biomuta DOID:363 / uterine cancer [ icgc ]
Y594 H594 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
R1375 G1375 Biomuta DOID:10534 / stomach cancer [ icgc ]
R1384 Q1384 Biomuta DOID:1324 / lung cancer [ cosmic ]
R1384 * Biomuta DOID:9256 / colorectal cancer [ cosmic ]