Protein Information

Cytoscape View


UniProt AC / UniProt ID O54967 / ACK1_MOUSE
Protein Name Activated CDC42 kinase 1
Gene Name Name: Tnk2
Synonyms:Ack1;
Organism Mus musculus (Mouse)

PRO ID PR:O54967
DAG View
PRO Name activated CDC42 kinase 1 (mouse)
Definition An activated CDC42 kinase 1 that is encoded in the genome of mouse.
Short Label mTNK2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O54967 (Tnk2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T33 Phosphorylation PhosphoSitePlus
Y40 Phosphorylation PhosphoSitePlus
S102 Phosphorylation PhosphoSitePlus
T104 Phosphorylation PhosphoSitePlus
T113 Phosphorylation PhosphoSitePlus   UniProt 21183079
K131 Ubiquitination PhosphoSitePlus
Y284 Phosphorylation PhosphoSitePlus   RLIMS-P 21309750, 29386546
P518 Phosphorylation UniProt 18034455
T528 Phosphorylation PhosphoSitePlus
T532 Phosphorylation PhosphoSitePlus
Y533 Phosphorylation PhosphoSitePlus   UniProt 21169560
K565 Ubiquitination PhosphoSitePlus
T618 Phosphorylation PhosphoSitePlus
S622 Phosphorylation PhosphoSitePlus
Y650 Phosphorylation PhosphoSitePlus
T741 Phosphorylation PhosphoSitePlus
S743 Phosphorylation PhosphoSitePlus
S772 Phosphorylation PhosphoSitePlus
S776 Phosphorylation PhosphoSitePlus
S789 Phosphorylation PhosphoSitePlus
S800 Phosphorylation PhosphoSitePlus
S825 Phosphorylation PhosphoSitePlus
T829 O-Glycosylation GlyGen 32782141, 34678516
T832 O-Glycosylation GlyGen   PhosphoSitePlus 34678516, 32848054, 32782141, ...30059200, 22517741, 22645316, 35822049
T833 O-Glycosylation GlyGen   PhosphoSitePlus 34678516, 32848054, 32782141, ...30059200, 22517741, 22645316, 35822049
S835 O-Glycosylation GlyGen 22645316
Y842 Phosphorylation phospho.ELM   PhosphoSitePlus 14739304
T844 Phosphorylation PhosphoSitePlus
R854 Methylation PhosphoSitePlus   UniProt 24129315
S870 Phosphorylation PhosphoSitePlus
S871 Phosphorylation PhosphoSitePlus
Y874 Phosphorylation PhosphoSitePlus
Y875 Phosphorylation PhosphoSitePlus
S896 Phosphorylation PhosphoSitePlus
S951 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T517 Phosphorylation PhosphoSitePlus
Y518 Phosphorylation PhosphoSitePlus
S522 Phosphorylation PhosphoSitePlus


O54967 (Tnk2) as PTM Enzyme



Substrate Site Score Source PMID
P31750 (Akt1) Y176 PhosphoSitePlus 20333297