iPTMnet Report for O43933 (PEX1)
Protein Information
UniProt AC / UniProt ID | O43933 / PEX1_HUMAN |
Protein Name | Peroxisomal ATPase PEX1 |
Gene Name | Name: PEX1 |
Organism | Homo sapiens (Human) |
PRO ID | PR:O43933 |
PRO Name | peroxisomal ATPase PEX1 (human) |
Definition | A peroxisomal ATPase PEX1 that is encoded in the genome of human. |
Short Label | hPEX1 |
Category | organism-gene |
O43933 (PEX1) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K191 | Ubiquitination | score1 | PhosphoSitePlus | |||
K198 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y202 | Phosphorylation | score1 | PhosphoSitePlus | |||
K211 | Ubiquitination | score1 | PhosphoSitePlus | |||
K260 | Ubiquitination | score1 | PhosphoSitePlus | |||
S264 | Phosphorylation | score1 | PhosphoSitePlus | |||
K274 | Ubiquitination | score1 | PhosphoSitePlus | |||
S278 | Phosphorylation | score1 | PhosphoSitePlus | |||
K279 | Ubiquitination | score1 | PhosphoSitePlus | |||
K291 | Ubiquitination | score1 | PhosphoSitePlus | |||
K337 | Ubiquitination | score1 | PhosphoSitePlus | |||
K342 | Ubiquitination | score1 | PhosphoSitePlus | |||
K349 | Ubiquitination | score1 | PhosphoSitePlus | |||
S354 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
K357 | Ubiquitination | score1 | PhosphoSitePlus | |||
K402 | Ubiquitination | score1 | PhosphoSitePlus | |||
K411 | Ubiquitination | score1 | PhosphoSitePlus | |||
T438 | Phosphorylation | score1 | PhosphoSitePlus | |||
K446 | Ubiquitination | score1 | PhosphoSitePlus | |||
K455 | Ubiquitination | score1 | PhosphoSitePlus | |||
K513 | Ubiquitination | score1 | PhosphoSitePlus | |||
S541 | Phosphorylation | score1 | PhosphoSitePlus | |||
S585 | Phosphorylation | score1 | PhosphoSitePlus | |||
K610 | Ubiquitination | score1 | PhosphoSitePlus | |||
K614 | Ubiquitination | score1 | PhosphoSitePlus | |||
K619 | Ubiquitination | score1 | PhosphoSitePlus | |||
K630 | Ubiquitination | score1 | PhosphoSitePlus | |||
K756 | Ubiquitination | score1 | PhosphoSitePlus | |||
K763 | Ubiquitination | score1 | PhosphoSitePlus | |||
K774 | Ubiquitination | score1 | PhosphoSitePlus | |||
K806 | Ubiquitination | score1 | PhosphoSitePlus | |||
T810 | Phosphorylation | score1 | PhosphoSitePlus | |||
T811 | Phosphorylation | score1 | PhosphoSitePlus | |||
K816 | Ubiquitination | score1 | PhosphoSitePlus | |||
K833 | Ubiquitination | score1 | PhosphoSitePlus | |||
K841 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y880 | Phosphorylation | score1 | PhosphoSitePlus | |||
T885 | Phosphorylation | score1 | PhosphoSitePlus | |||
K887 | Ubiquitination | score1 | PhosphoSitePlus | |||
K906 | Ubiquitination | score1 | PhosphoSitePlus | |||
K913 | Ubiquitination | score1 | PhosphoSitePlus | |||
K933 | Ubiquitination | score1 | PhosphoSitePlus | |||
K1001 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1172 | Phosphorylation | score1 | PhosphoSitePlus | |||
T1179 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus | 18669648 | ||
S1181 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 17525332, 23186163, 18669648 | ||
T1189 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1201 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1204 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y1207 | Phosphorylation | score1 | PhosphoSitePlus | |||
S1209 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 20068231 | ||
S1211 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 18669648, 23186163 | ||
S1216 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1224 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1259 | Phosphorylation | score1 | PhosphoSitePlus | |||
K1264 | Ubiquitination | score1 | PhosphoSitePlus | |||
S1270 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K198 | R198 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
Y202 | H202 | Biomuta | DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
K211 | R211 | Biomuta | DOID:1793 / pancreatic cancer [ cosmic ] | |
K274 | R274 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K337 | M337 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
K357 | N357 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
T438 | N438 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
S541 | N541 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
S585 | C585 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
K614 | E614 | Biomuta | DOID:1793 / pancreatic cancer [ icgc ] | |
K763 | N763 | Biomuta | DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ] | |
K833 | T833 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K887 | N887 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K906 | R906 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
S1216 | Y1216 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |