Protein Information

Cytoscape View


UniProt AC / UniProt ID O43918 / AIRE_HUMAN
Protein Name Autoimmune regulator
Gene Name Name: AIRE
Synonyms:APECED;
Organism Homo sapiens (Human)

PRO ID PR:O43918
DAG View
PRO Name autoimmune regulator (human)
Definition An autoimmune regulator that is encoded in the genome of human.
Short Label hAIRE
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43918 (AIRE) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T68 Phosphorylation P78527 (PRKDC) neXtProt   PhosphoSitePlus   RLIMS-P 17997173
T147 Phosphorylation PhosphoSitePlus
S156 Phosphorylation P78527 (PRKDC) neXtProt   PhosphoSitePlus   RLIMS-P 17997173
T183 Phosphorylation PhosphoSitePlus
S187 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T183 N183 Biomuta DOID:5041 / esophageal cancer [ icgc ]