iPTMnet Report for O43909 (EXTL3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43909 / EXTL3_HUMAN
Protein Name Exostosin-like 3
Gene Name Name: EXTL3
Synonyms:EXTL1L,EXTR1,KIAA0519;
Organism Homo sapiens (Human)

PRO ID PR:O43909
DAG View
PRO Name exostosin-like 3 (human)
Definition An exostosin-like 3 that is encoded in the genome of human.
Short Label hEXTL3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43909 (EXTL3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y4 Phosphorylation PhosphoSitePlus
K99 Ubiquitination PhosphoSitePlus
K118 Acetylation PhosphoSitePlus
K125 Acetylation PhosphoSitePlus
T138 O-Glycosylation GlyGen 25813380
Y142 Phosphorylation PhosphoSitePlus
N290 N-Glycosylation GlyGen   UniProt 29346724, 24190977
S389 Phosphorylation PhosphoSitePlus
K401 Acetylation PhosphoSitePlus
S499 Phosphorylation PhosphoSitePlus
S501 Phosphorylation PhosphoSitePlus
T563 O-Glycosylation GlyGen 30459171
N592 N-Glycosylation GlyGen   UniProt 29346724, 35676258
T594 O-Glycosylation GlyGen 35289036
T596 O-Glycosylation GlyGen 35289036
N790 N-Glycosylation GlyGen   UniProt 35676258


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K125 N125 Biomuta DOID:1793 / pancreatic cancer [ icgc ]
S389 N389 Biomuta DOID:4159 / skin cancer [ cosmic ]
S501 F501 Biomuta DOID:4159 / skin cancer [ cosmic ]
N592 S592 Biomuta DOID:4606 / bile duct cancer [ cosmic ]