iPTMnet Report for O43903 (GAS2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43903 / GAS2_HUMAN
Protein Name Growth arrest-specific protein 2
Gene Name Name: GAS2
Organism Homo sapiens (Human)

PRO ID PR:O43903
DAG View
PRO Name growth arrest-specific protein 2 (human)
Definition A growth arrest-specific protein 2 that is encoded in the genome of human.
Short Label hGAS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43903 (GAS2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K86 Ubiquitination PhosphoSitePlus
T100 Phosphorylation PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
S106 Phosphorylation PhosphoSitePlus
S183 Phosphorylation PhosphoSitePlus
S185 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S187 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 24275569
S190 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T258 Phosphorylation PhosphoSitePlus
Y262 Phosphorylation PhosphoSitePlus
S282 Phosphorylation PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S185 Phosphorylation HPRD 18669648
S187 Phosphorylation HPRD 18669648
S190 Phosphorylation HPRD 18669648
S288 Phosphorylation HPRD 20166139


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K86 E86 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T100 S100 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S104 W104 Biomuta DOID:1612 / breast cancer [ cosmic ] DOID:5041 / esophageal cancer [ cosmic, icgc ]
S104 L104 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S106 C106 Biomuta DOID:4159 / skin cancer [ cosmic ]
S187 Y187 Biomuta DOID:363 / uterine cancer [ icgc ]
S190 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
Y262 C262 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y262 * Biomuta DOID:2394 / ovarian cancer [ cosmic ]
S282 Y282 Biomuta DOID:1324 / lung cancer [ cosmic ]