iPTMnet Report for O43900 (PRICKLE3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43900 / PRIC3_HUMAN
Protein Name Prickle planar cell polarity protein 3
Gene Name Name: PRICKLE3
Synonyms:LMO6;
Organism Homo sapiens (Human)

PRO ID PR:O43900
DAG View
PRO Name prickle planar cell polarity protein 3 (human)
Definition A prickle planar cell polarity protein 3 that is encoded in the genome of human.
Short Label hPRICKLE3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43900 (PRICKLE3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R4 Methylation PhosphoSitePlus
S80 Phosphorylation PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
K130 Ubiquitination PhosphoSitePlus
Y303 Phosphorylation PhosphoSitePlus
S367 Phosphorylation PhosphoSitePlus
S370 Phosphorylation PhosphoSitePlus
S378 Phosphorylation PhosphoSitePlus
S381 Phosphorylation PhosphoSitePlus
S383 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T388 Phosphorylation PhosphoSitePlus
K410 Ubiquitination PhosphoSitePlus
S413 Phosphorylation PhosphoSitePlus
T414 Phosphorylation PhosphoSitePlus
S437 Phosphorylation PhosphoSitePlus
S453 Phosphorylation PhosphoSitePlus
S475 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336
T489 Phosphorylation PhosphoSitePlus
S491 Phosphorylation PhosphoSitePlus   UniProt 23186163
S502 Phosphorylation IEDB   phospho.ELM   PhosphoSitePlus 15302935, 17081983, 33936100
S542 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S367 Phosphorylation HPRD 16964243
S383 Phosphorylation HPRD 18669648
S502 Phosphorylation HPRD 15302935


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S381 R381 Biomuta DOID:363 / uterine cancer [ cosmic ]
S413 N413 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T414 K414 Biomuta DOID:4362 / cervical cancer [ cosmic ]
S542 L542 Biomuta DOID:1324 / lung cancer [ cosmic ]