Protein Information

Cytoscape View


UniProt AC / UniProt ID O43897 / TLL1_HUMAN
Protein Name Tolloid-like protein 1 precursor
Gene Name Name: TLL1
Synonyms:TLL;
Organism Homo sapiens (Human)

PRO ID PR:O43897
DAG View
PRO Name tolloid-like protein 1 (human)
Definition A tolloid-like protein 1 that is encoded in the genome of human.
Short Label hTLL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43897 (TLL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y109 Phosphorylation PhosphoSitePlus
N125 N-Glycosylation GlyGen 23090970, 24190977
K131 Ubiquitination PhosphoSitePlus
T153 Phosphorylation PhosphoSitePlus
N169 N-Glycosylation GlyGen 29741879
K334 Ubiquitination PhosphoSitePlus
N390 N-Glycosylation GlyGen 23090970, 24190977
T702 Phosphorylation PhosphoSitePlus
T860 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y109 N109 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T153 K153 Biomuta DOID:263 / kidney cancer [ cosmic ]
T153 M153 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
N169 K169 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
N390 S390 Biomuta DOID:9256 / colorectal cancer [ cosmic ]