iPTMnet Report for O43896 (KIF1C)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43896 / KIF1C_HUMAN
Protein Name Kinesin-like protein KIF1C
Gene Name Name: KIF1C
Synonyms:KIAA0706;
Organism Homo sapiens (Human)

PRO ID PR:O43896
DAG View
PRO Name kinesin-like protein KIF1C (human)
Definition A kinesin-like protein KIF1C that is encoded in the genome of human.
Short Label hKIF1C
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43896 (KIF1C) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S162 Phosphorylation PhosphoSitePlus
T222 Phosphorylation PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
S257 Phosphorylation PhosphoSitePlus
S258 Phosphorylation PhosphoSitePlus
K266 Ubiquitination PhosphoSitePlus
S274 Phosphorylation PhosphoSitePlus
T276 Phosphorylation PhosphoSitePlus
T277 Phosphorylation PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus   UniProt 23186163
S326 Phosphorylation PhosphoSitePlus
Y332 Phosphorylation PhosphoSitePlus
S385 Phosphorylation PhosphoSitePlus
S412 Phosphorylation PhosphoSitePlus
T489 Phosphorylation HPRD   PhosphoSitePlus 20068231
S494 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 23186163, 16964243, 20068231
K658 Ubiquitination PhosphoSitePlus
Y671 Phosphorylation PhosphoSitePlus
S674 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 21406692, 17081983, ...20068231
S676 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 21406692, 20068231
S680 Phosphorylation HPRD   PhosphoSitePlus 19651622
T702 Phosphorylation PhosphoSitePlus
T703 Phosphorylation PhosphoSitePlus
Y726 Phosphorylation PhosphoSitePlus
K788 Ubiquitination PhosphoSitePlus
S817 Phosphorylation PhosphoSitePlus
K839 Ubiquitination PhosphoSitePlus
K848 Ubiquitination PhosphoSitePlus
S915 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231, 24275569
S919 Phosphorylation PhosphoSitePlus
R948 Methylation PhosphoSitePlus
S955 Phosphorylation PhosphoSitePlus
R958 Methylation PhosphoSitePlus
R963 Methylation PhosphoSitePlus
S996 Phosphorylation PhosphoSitePlus
S1022 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S1033 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 17081983, 20068231
R1041 Methylation PhosphoSitePlus   UniProt 24129315
K1057 Methylation PhosphoSitePlus
R1072 Methylation PhosphoSitePlus
R1077 Methylation PhosphoSitePlus
Y1078 Phosphorylation PhosphoSitePlus
Y1081 Phosphorylation PhosphoSitePlus
T1082 Phosphorylation HPRD   PhosphoSitePlus 19413330
T1083 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19664994, 18220336
S1092 Phosphorylation P68400 (CSNK2A1) , P19784 (CSNK2A2) HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17081983, 18669648, 19690332, ...20068231, 10559254


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S162 I162 Biomuta DOID:3571 / liver cancer [ cosmic ]
S257 F257 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
K266 N266 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
T276 I276 Biomuta DOID:1612 / breast cancer [ cosmic ]
S326 C326 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y726 F726 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K839 N839 Biomuta DOID:3571 / liver cancer [ cosmic ]
S915 W915 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S915 L915 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R948 W948 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
R958 Q958 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
R958 W958 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
R963 C963 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic, icgc ]
R1041 Q1041 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
R1072 W1072 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic ] DOID:1319 / brain cancer [ cosmic ]
T1083 S1083 Biomuta DOID:4159 / skin cancer [ cosmic ]