iPTMnet Report for O43895 (XPNPEP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43895 / XPP2_HUMAN
Protein Name Xaa-Pro aminopeptidase 2 precursor
Gene Name Name: XPNPEP2
Organism Homo sapiens (Human)

PRO ID PR:O43895
DAG View
PRO Name Xaa-Pro aminopeptidase 2 (human)
Definition An Xaa-Pro aminopeptidase 2 that is encoded in the genome of human.
Short Label hXPNPEP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43895 (XPNPEP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y81 Phosphorylation PhosphoSitePlus
S221 Phosphorylation PhosphoSitePlus
Y379 Phosphorylation PhosphoSitePlus
S422 Phosphorylation PhosphoSitePlus
Y431 Phosphorylation PhosphoSitePlus
S432 Phosphorylation PhosphoSitePlus
S442 Phosphorylation PhosphoSitePlus
Y617 Phosphorylation HPRD   PhosphoSitePlus 20166139
Y618 Phosphorylation HPRD   PhosphoSitePlus 20166139


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y379 F379 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y379 C379 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
Y431 C431 Biomuta DOID:9256 / colorectal cancer [ cosmic ]