iPTMnet Report for O43837 (IDH3B)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43837 / IDH3B_HUMAN
Protein Name Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial precursor
Gene Name Name: IDH3B
Organism Homo sapiens (Human)

PRO ID PR:O43837
DAG View
PRO Name isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (human)
Definition An isocitrate dehydrogenase [NAD] subunit beta, mitochondrial that is encoded in the genome of human.
Short Label hIDH3B
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43837 (IDH3B) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S5 Phosphorylation PhosphoSitePlus
T11 Phosphorylation PhosphoSitePlus
K96 Acetylation PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
K105 Ubiquitination PhosphoSitePlus
T117 Phosphorylation PhosphoSitePlus
Y121 Phosphorylation PhosphoSitePlus
K135 Acetylation PhosphoSitePlus
K135 Ubiquitination PhosphoSitePlus
K146 Acetylation PhosphoSitePlus
T167 Phosphorylation PhosphoSitePlus
Y171 Phosphorylation PhosphoSitePlus
S172 Phosphorylation PhosphoSitePlus
S173 Phosphorylation PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus
K199 Acetylation PhosphoSitePlus   UniProt 19608861
K199 Ubiquitination PhosphoSitePlus
K207 Acetylation PhosphoSitePlus
K212 Ubiquitination PhosphoSitePlus
K218 Acetylation PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
K242 Ubiquitination PhosphoSitePlus
S330 Phosphorylation PhosphoSitePlus
K350 Acetylation PhosphoSitePlus
Y366 Phosphorylation PhosphoSitePlus
T368 Phosphorylation PhosphoSitePlus
T369 Phosphorylation PhosphoSitePlus
K374 Acetylation PhosphoSitePlus
S375 Phosphorylation PhosphoSitePlus
K383 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T360 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K96 Q96 Biomuta DOID:3571 / liver cancer [ cosmic ]
T369 S369 Biomuta DOID:4159 / skin cancer [ cosmic ]