Protein Information

Cytoscape View


UniProt AC / UniProt ID O43819 / SCO2_HUMAN
Protein Name Protein SCO2 homolog, mitochondrial precursor
Gene Name Name: SCO2
Organism Homo sapiens (Human)

PRO ID PR:O43819
DAG View
PRO Name protein SCO2 homolog, mitochondrial (human)
Definition A protein SCO2, mitochondrial that is encoded in the genome of human.
Short Label hSCO2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43819 (SCO2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation PhosphoSitePlus
T9 Phosphorylation PhosphoSitePlus
S15 Phosphorylation PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
S39 Phosphorylation PhosphoSitePlus
T46 Phosphorylation PhosphoSitePlus
T59 Phosphorylation PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
R243 Methylation PhosphoSitePlus
S266 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T9 A9 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
T46 I46 Biomuta DOID:10534 / stomach cancer [ cosmic ]
R243 W243 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]