iPTMnet Report for O43815 (STRN)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43815 / STRN_HUMAN
Protein Name Striatin
Gene Name Name: STRN
Organism Homo sapiens (Human)

PRO ID PR:O43815
DAG View
PRO Name striatin (human)
Definition A striatin that is encoded in the genome of human.
Short Label hSTRN
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43815 (STRN) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K110 Ubiquitination PhosphoSitePlus
Y135 Phosphorylation PhosphoSitePlus
S137 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T143 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T172 Phosphorylation PhosphoSitePlus
T174 Phosphorylation PhosphoSitePlus
S190 Phosphorylation PhosphoSitePlus
K200 Acetylation PhosphoSitePlus
S204 Phosphorylation PhosphoSitePlus
K214 Acetylation PhosphoSitePlus
K221 Acetylation PhosphoSitePlus
S227 Phosphorylation PhosphoSitePlus   UniProt 23186163
S229 Phosphorylation PhosphoSitePlus   UniProt 23186163
S245 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 19369195, 23186163, 18669648, ...24275569, 19690332
S259 Phosphorylation PhosphoSitePlus   UniProt 23186163
S264 Phosphorylation PhosphoSitePlus
T265 Phosphorylation PhosphoSitePlus
T293 Phosphorylation PhosphoSitePlus
S294 Phosphorylation PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
T308 Phosphorylation PhosphoSitePlus
K353 Ubiquitination PhosphoSitePlus
S373 Phosphorylation PhosphoSitePlus
S376 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S378 Phosphorylation phospho.ELM 18669648
T400 Phosphorylation PhosphoSitePlus
S404 Phosphorylation PhosphoSitePlus
S405 Phosphorylation PhosphoSitePlus
Y440 Phosphorylation PhosphoSitePlus
K456 Ubiquitination PhosphoSitePlus
T458 Phosphorylation PhosphoSitePlus
Y510 Phosphorylation PhosphoSitePlus
T511 Phosphorylation PhosphoSitePlus
C665 S-Nitrosylation dbSNO 26338901
R686 Methylation PhosphoSitePlus
K689 Acetylation PhosphoSitePlus
K689 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S137 Phosphorylation HPRD 18669648, 18452278
T143 Phosphorylation HPRD 18669648, 18452278
S245 Phosphorylation HPRD 19413330, 19664994, 18452278, ...19651622, 18669648, 19415658, 20068231
S376 Phosphorylation HPRD 18669648, 19664994
S378 Phosphorylation HPRD 18669648
S586 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K110 E110 Biomuta DOID:3571 / liver cancer [ cosmic ]
T143 I143 Biomuta DOID:3571 / liver cancer [ cosmic ]
T174 I174 Biomuta DOID:363 / uterine cancer [ icgc ]
K200 N200 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K221 T221 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S259 N259 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K353 N353 Biomuta DOID:363 / uterine cancer [ icgc ] DOID:10534 / stomach cancer [ cosmic ]
S404 F404 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K456 T456 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
Y510 * Biomuta DOID:4159 / skin cancer [ cosmic ]
R686 M686 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]