iPTMnet Report for O43813 (LANCL1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43813 / LANC1_HUMAN
Protein Name Glutathione S-transferase LANCL1
Gene Name Name: LANCL1
Synonyms:GPR69A;
Organism Homo sapiens (Human)

PRO ID PR:O43813
DAG View
PRO Name glutathione S-transferase LANCL1 (human)
Definition A glutathione S-transferase LANCL1 that is encoded in the genome of human.
Short Label hLANCL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43813 (LANCL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
Y10 Phosphorylation PhosphoSitePlus
K15 Acetylation PhosphoSitePlus
K15 Ubiquitination PhosphoSitePlus
Y21 Phosphorylation PhosphoSitePlus
T29 O-Glycosylation GlyGen 23301498, 34019948, 29351928
T29 Phosphorylation PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
S95 Phosphorylation PhosphoSitePlus
T100 Phosphorylation PhosphoSitePlus
K101 Acetylation PhosphoSitePlus
K101 Ubiquitination PhosphoSitePlus
K123 Acetylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
T135 Phosphorylation PhosphoSitePlus
K142 Acetylation PhosphoSitePlus   UniProt 19608861
K142 Ubiquitination PhosphoSitePlus
Y153 Phosphorylation PhosphoSitePlus
K173 Ubiquitination PhosphoSitePlus
M206 Methylation IEDB 25880248
K245 Ubiquitination PhosphoSitePlus
Y250 Phosphorylation PhosphoSitePlus
Y319 Phosphorylation PhosphoSitePlus
Y330 Phosphorylation PhosphoSitePlus
Y336 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K142 Q142 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K142 E142 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
M206 R206 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K245 N245 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y250 C250 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]