iPTMnet Report for O43790 (KRT86)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43790 / KRT86_HUMAN
Protein Name Keratin, type II cuticular Hb6
Gene Name Name: KRT86
Synonyms:KRTHB6;
Organism Homo sapiens (Human)

PRO ID PR:O43790
DAG View
PRO Name keratin, type II cuticular Hb6 (human)
Definition A keratin, type II cuticular Hb6 that is encoded in the genome of human.
Short Label hKRT86
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43790 (KRT86) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S47 Phosphorylation PhosphoSitePlus
S49 Phosphorylation PhosphoSitePlus
K132 Acetylation PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
K193 Methylation PhosphoSitePlus
T203 Phosphorylation PhosphoSitePlus
K222 Methylation PhosphoSitePlus
Y243 Phosphorylation PhosphoSitePlus
Y282 Phosphorylation PhosphoSitePlus
Y297 Phosphorylation PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus
K305 Ubiquitination PhosphoSitePlus
T307 Phosphorylation PhosphoSitePlus
T314 Phosphorylation PhosphoSitePlus
T318 Phosphorylation PhosphoSitePlus
K319 Ubiquitination PhosphoSitePlus
K340 Ubiquitination PhosphoSitePlus
K345 Acetylation PhosphoSitePlus
K345 Ubiquitination PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
K377 Methylation PhosphoSitePlus
K377 Ubiquitination PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
Y389 Phosphorylation PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus
S455 Phosphorylation PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
T466 Phosphorylation PhosphoSitePlus
S482 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y243 C243 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K340 M340 Biomuta DOID:1324 / lung cancer [ cosmic ]
K377 E377 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]