Protein Information

Cytoscape View


UniProt AC / UniProt ID O43781 / DYRK3_HUMAN
Protein Name Dual specificity tyrosine-phosphorylation-regulated kinase 3
Gene Name Name: DYRK3
Organism Homo sapiens (Human)

PRO ID PR:O43781
DAG View
PRO Name dual specificity tyrosine-phosphorylation-regulated kinase 3 (human)
Definition A dual specificity tyrosine-phosphorylation-regulated kinase 3 that is encoded in the genome of human.
Short Label hDYRK3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43781 (DYRK3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y209 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455
S350 Phosphorylation PhosphoSitePlus
T351 Phosphorylation PhosphoSitePlus
Y367 Phosphorylation PhosphoSitePlus
T368 Phosphorylation PhosphoSitePlus
Y369 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
S372 Phosphorylation PhosphoSitePlus
Y451 Phosphorylation PhosphoSitePlus
S453 Phosphorylation PhosphoSitePlus
T455 Phosphorylation PhosphoSitePlus
T456 Phosphorylation PhosphoSitePlus
S469 Phosphorylation PhosphoSitePlus
S480 Phosphorylation PhosphoSitePlus
K481 Acetylation PhosphoSitePlus
T485 Phosphorylation PhosphoSitePlus
K488 Acetylation PhosphoSitePlus
Y493 Phosphorylation PhosphoSitePlus
T532 Phosphorylation PhosphoSitePlus
S537 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y209 Phosphorylation HPRD 15592455
Y369 Phosphorylation HPRD 18083107
Site PTM Type PTM Enzyme Score Source PMID
Y189 Phosphorylation HPRD 15592455
Y349 Phosphorylation HPRD 18083107


O43781 (DYRK3) as PTM Enzyme



Substrate Site Score Source PMID
P16220 (CREB1) S133 phospho.ELM 12356771
Q96B36 (AKT1S1) T246 neXtProt   PhosphoSitePlus   UniProt 23415227, 18669648
Q96EB6 (SIRT1) T530 UniProt 19690332