iPTMnet Report for O43736 (ITM2A)
Protein Information
UniProt AC / UniProt ID | O43736 / ITM2A_HUMAN |
Protein Name | Integral membrane protein 2A |
Gene Name | Name: ITM2A ORFNames:UNQ603/PRO1189; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O43736 |
PRO Name | integral membrane protein 2A (human) |
Definition | An integral membrane protein 2A that is encoded in the genome of human. |
Short Label | hITM2A |
Category | organism-gene |
O43736 (ITM2A) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K3 | Acetylation | score1 | IEDB | 34357683 | ||
K3 | Ubiquitination | score1 | PhosphoSitePlus | |||
T8 | Phosphorylation | score1 | PhosphoSitePlus | |||
T10 | Phosphorylation | score1 | PhosphoSitePlus | |||
K14 | Ubiquitination | score1 | PhosphoSitePlus | |||
T35 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 31438969 | ||
K37 | Ubiquitination | score1 | PhosphoSitePlus | |||
T112 | Phosphorylation | score1 | PhosphoSitePlus | |||
K182 | Ubiquitination | score1 | PhosphoSitePlus | |||
K238 | Ubiquitination | score1 | PhosphoSitePlus | |||
K243 | Ubiquitination | score1 | PhosphoSitePlus | |||
C244 | Methylation | score1 | IEDB | 31844290 | ||
K246 | Ubiquitination | score1 | PhosphoSitePlus | |||
K259 | Ubiquitination | score1 | PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K37 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T8 | A8 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
T35 | N35 | Biomuta | DOID:2394 / ovarian cancer [ icgc ] | |
K182 | Q182 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
K243 | T243 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K246 | N246 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
K259 | N259 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] |