iPTMnet Report for O43736 (ITM2A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43736 / ITM2A_HUMAN
Protein Name Integral membrane protein 2A
Gene Name Name: ITM2A
ORFNames:UNQ603/PRO1189;
Organism Homo sapiens (Human)

PRO ID PR:O43736
DAG View
PRO Name integral membrane protein 2A (human)
Definition An integral membrane protein 2A that is encoded in the genome of human.
Short Label hITM2A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43736 (ITM2A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K3 Acetylation IEDB 34357683
K3 Ubiquitination PhosphoSitePlus
T8 Phosphorylation PhosphoSitePlus
T10 Phosphorylation PhosphoSitePlus
K14 Ubiquitination PhosphoSitePlus
T35 Phosphorylation PhosphoSitePlus   RLIMS-P 31438969
K37 Ubiquitination PhosphoSitePlus
T112 Phosphorylation PhosphoSitePlus
K182 Ubiquitination PhosphoSitePlus
K238 Ubiquitination PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
C244 Methylation IEDB 31844290
K246 Ubiquitination PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
K37 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T8 A8 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T35 N35 Biomuta DOID:2394 / ovarian cancer [ icgc ]
K182 Q182 Biomuta DOID:4159 / skin cancer [ cosmic ]
K243 T243 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K246 N246 Biomuta DOID:363 / uterine cancer [ icgc ]
K259 N259 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]