iPTMnet Report for O43699 (SIGLEC6)
Protein Information
UniProt AC / UniProt ID | O43699 / SIGL6_HUMAN |
Protein Name | Sialic acid-binding Ig-like lectin 6 precursor |
Gene Name | Name: SIGLEC6 Synonyms:CD33L,CD33L1,OBBP1; |
Organism | Homo sapiens (Human) |
PRO ID | PR:O43699 |
PRO Name | sialic acid-binding Ig-like lectin 6 (human) |
Definition | A sialic acid-binding Ig-like lectin 6 that is encoded in the genome of human. |
Short Label | hSIGLEC6 |
Category | organism-gene |
O43699 (SIGLEC6) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
N103 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
S107 | Phosphorylation | score1 | PhosphoSitePlus | |||
K136 | Acetylation | score1 | PhosphoSitePlus | |||
N233 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
N258 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
Y426 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y446 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S107 | N107 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K136 | N136 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
Y426 | C426 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |