iPTMnet Report for O43657 (TSPAN6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43657 / TSN6_HUMAN
Protein Name Tetraspanin-6
Gene Name Name: TSPAN6
Synonyms:TM4SF6;ORFNames:UNQ767/PRO1560;
Organism Homo sapiens (Human)

PRO ID PR:O43657
DAG View
PRO Name tetraspanin-6 (human)
Definition A tetraspanin-6 that is encoded in the genome of human.
Short Label hTSPAN6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43657 (TSPAN6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y49 Phosphorylation PhosphoSitePlus
K123 Methylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K131 Ubiquitination PhosphoSitePlus
N134 N-Glycosylation GlyGen 23090970, 24190977
K146 Ubiquitination PhosphoSitePlus
R160 Methylation PhosphoSitePlus
T163 Phosphorylation PhosphoSitePlus
Y167 Phosphorylation PhosphoSitePlus
Y168 Phosphorylation PhosphoSitePlus
S169 Phosphorylation PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
Y242 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K123 N123 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K146 M146 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]