iPTMnet Report for O43623 (SNAI2)
Protein Information
| UniProt AC / UniProt ID | O43623 / SNAI2_HUMAN |
| Protein Name | Zinc finger protein SNAI2 |
| Gene Name | Name: SNAI2 Synonyms:SLUG,SLUGH; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O43623 |
| PRO Name | zinc finger protein SNAI2 (human) |
| Definition | A zinc finger protein SNAI2 that is encoded in the genome of human. |
| Short Label | hSNAI2 |
| Category | organism-gene |
DAG ViewO43623 (SNAI2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S4 | Phosphorylation | score0 | RLIMS-P | 22567133 | ||
| K8 | Acetylation | score1 | PhosphoSitePlus | |||
| S54 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S87 | Phosphorylation | P28482 (MAPK1) | score3 | PhosphoSitePlus RLIMS-P | 25855378 | |
| S92 | Phosphorylation | P49841 (GSK3B) | score3 | PhosphoSitePlus | 22727060, 23851495 | |
| S96 | Phosphorylation | P49841 (GSK3B) | score3 | PhosphoSitePlus | 22727060, 23851495 | |
| S100 | Phosphorylation | P49841 (GSK3B) | score3 | PhosphoSitePlus | 22727060, 23851495 | |
| S104 | Phosphorylation | P28482 (MAPK1) , P49841 (GSK3B) | score3 | PhosphoSitePlus | 22727060, 23851495, 25855378 | |
| K116 | Acetylation | score1 | PhosphoSitePlus | |||
| T136 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S158 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 29849120 | ||
| C161 | Methylation | score1 | IEDB | 31844290 | ||
| K166 | Acetylation | score1 | PhosphoSitePlus | |||
| K175 | Ubiquitination | score1 | PhosphoSitePlus | |||
| C190 | Methylation | score1 | IEDB | 31844290 | ||
| T206 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T208 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 35859006 | ||
| K211 | Acetylation | score1 | PhosphoSitePlus | |||
| S247 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S251 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S254 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 29849120 |
PTM-dependent PPI
|
PTM type | Substrate | Site | Interactant | Association type | Source | PMID |
|---|---|---|---|---|---|---|---|
| Phosphorylation | Q04917 (YWHAH) | S25 | O43623 (SNAI2) | unknown | eFIP | 33116123 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S4 | F4 | Biomuta | DOID:4159 / skin cancer [ cosmic ] | |
| K8 | N8 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| K8 | E8 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| S158 | Y158 | Biomuta | DOID:4362 / cervical cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
| C161 | Y161 | Biomuta | DOID:1324 / lung cancer [ cosmic, icgc ] | |
| K166 | N166 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| K175 | E175 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S251 | C251 | Biomuta | DOID:184 / bone cancer [ cosmic ] |
