iPTMnet Report for O43615 (TIMM44)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43615 / TIM44_HUMAN
Protein Name Mitochondrial import inner membrane translocase subunit TIM44 precursor
Gene Name Name: TIMM44
Synonyms:MIMT44,TIM44;
Organism Homo sapiens (Human)

PRO ID PR:O43615
DAG View
PRO Name mitochondrial import inner membrane translocase subunit TIM44 (human)
Definition A mitochondrial import inner membrane translocase subunit TIM44 that is encoded in the genome of human.
Short Label hTIMM44
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43615 (TIMM44) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S61 Phosphorylation PhosphoSitePlus
S80 Phosphorylation RLIMS-P 33167377
T128 Phosphorylation PhosphoSitePlus   UniProt 23186163
K146 Ubiquitination PhosphoSitePlus
T155 O-Glycosylation GlyGen 34725712, 33465208
S159 O-Glycosylation GlyGen 33465208
S159 Phosphorylation PhosphoSitePlus
S162 O-Glycosylation GlyGen 33465208
S164 O-Glycosylation GlyGen 33465208
K165 Ubiquitination PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
S185 Phosphorylation PhosphoSitePlus
K187 Acetylation PhosphoSitePlus
K188 Acetylation PhosphoSitePlus
Y201 Phosphorylation PhosphoSitePlus
K217 Ubiquitination PhosphoSitePlus
K240 Ubiquitination PhosphoSitePlus
K246 Ubiquitination PhosphoSitePlus
K264 Ubiquitination PhosphoSitePlus
S268 Phosphorylation PhosphoSitePlus
T280 Phosphorylation PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus
Y435 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K146 N146 Biomuta DOID:1319 / brain cancer [ cosmic ]
S159 L159 Biomuta [ cosmic ]
S162 L162 Biomuta DOID:363 / uterine cancer [ icgc ]
K240 Q240 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T280 M280 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic ]
S292 Y292 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]