Protein Information

Cytoscape View

UniProt AC / UniProt ID O43613 / OX1R_HUMAN
Protein Name Orexin/Hypocretin receptor type 1
Gene Name Name: HCRTR1
Organism Homo sapiens (Human)

PRO ID PR:O43613
DAG View
PRO Name orexin/hypocretin receptor type 1 (human)
Definition An orexin/hypocretin receptor type 1 that is encoded in the genome of human.
Short Label hHCRTR1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O43613 (HCRTR1) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
Y27 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18083107
Y83 Phosphorylation PhosphoSitePlus
Y124 Phosphorylation PhosphoSitePlus
S129 O-Glycosylation GlyGen 29351928
S138 O-Glycosylation GlyGen 29351928
S138 Phosphorylation PhosphoSitePlus
S262 Phosphorylation PhosphoSitePlus   RLIMS-P 32827691
Y358 Phosphorylation PhosphoSitePlus 18198212
Y358 Phosphorylation P12931 (SRC) PhosphoSitePlus 18198212

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y27 N27 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]