iPTMnet Report for O43592 (XPOT)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43592 / XPOT_HUMAN
Protein Name Exportin-T
Gene Name Name: XPOT
Organism Homo sapiens (Human)

PRO ID PR:O43592
DAG View
PRO Name exportin-T (human)
Definition An exportin-T that is encoded in the genome of human.
Short Label hXPOT
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43592 (XPOT) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 22814378, 22223895
K172 Ubiquitination PhosphoSitePlus
K311 Ubiquitination PhosphoSitePlus
K316 Ubiquitination PhosphoSitePlus
T327 Phosphorylation PhosphoSitePlus
S432 Phosphorylation PhosphoSitePlus
K557 Ubiquitination PhosphoSitePlus
T622 Phosphorylation PhosphoSitePlus
K627 Acetylation PhosphoSitePlus
K629 Ubiquitination PhosphoSitePlus
K634 Acetylation PhosphoSitePlus   UniProt 19608861
K634 Ubiquitination PhosphoSitePlus
T661 Phosphorylation HPRD 20068231
K663 Ubiquitination PhosphoSitePlus
K668 Ubiquitination PhosphoSitePlus
K737 Ubiquitination PhosphoSitePlus
K859 Ubiquitination PhosphoSitePlus
C900 Methylation IEDB 31844290
K950 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K172 Q172 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K311 N311 Biomuta DOID:1324 / lung cancer [ cosmic ]
K316 R316 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K634 N634 Biomuta DOID:3571 / liver cancer [ cosmic ]