iPTMnet Report for O43567 (RNF13)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43567 / RNF13_HUMAN
Protein Name E3 ubiquitin-protein ligase RNF13 precursor
Gene Name Name: RNF13
Synonyms:RZF;
Organism Homo sapiens (Human)

PRO ID PR:O43567
DAG View
PRO Name E3 ubiquitin-protein ligase RNF13 (human)
Definition An E3 ubiquitin-protein ligase RNF13 that is encoded in the genome of human.
Short Label hRNF13
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43567 (RNF13) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
N70 N-Glycosylation GlyGen 24190977
N75 N-Glycosylation GlyGen 24190977
N88 N-Glycosylation GlyGen   UniProt 18794910, 24190977
S89 O-Glycosylation GlyGen 29485866, 28657654, 35254053
K107 Ubiquitination PhosphoSitePlus
K233 Ubiquitination PhosphoSitePlus
Y247 Phosphorylation PhosphoSitePlus
K252 Ubiquitination PhosphoSitePlus
K273 Ubiquitination PhosphoSitePlus
K275 Ubiquitination PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
T309 Phosphorylation PhosphoSitePlus
S319 Phosphorylation PhosphoSitePlus
T380 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S89 L89 Biomuta DOID:3571 / liver cancer [ cosmic, icgc ]
K252 R252 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
K273 E273 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T309 I309 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:4159 / skin cancer [ cosmic ]