iPTMnet Report for O43543 (XRCC2)
Protein Information
| UniProt AC / UniProt ID | O43543 / XRCC2_HUMAN |
| Protein Name | DNA repair protein XRCC2 |
| Gene Name | Name: XRCC2 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:O43543 |
| PRO Name | DNA repair protein XRCC2 (human) |
| Definition | A DNA repair protein XRCC2 that is encoded in the genome of human. |
| Short Label | hXRCC2 |
| Category | organism-gene |
DAG ViewO43543 (XRCC2) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S10 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
| T12 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K25 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y59 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K236 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K243 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S247 | Phosphorylation | score4 | HPRD phospho.ELM PhosphoSitePlus RLIMS-P | 17525332, 30566856 | ||
| S249 | Phosphorylation | score2 | HPRD phospho.ELM PhosphoSitePlus | 17525332 | ||
| K261 | Ubiquitination | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T12 | N12 | Biomuta | DOID:3571 / liver cancer [ cosmic ] |
