iPTMnet Report for O43505 (B4GAT1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43505 / B4GA1_HUMAN
Protein Name Beta-1,4-glucuronyltransferase 1
Gene Name Name: B4GAT1
Synonyms:B3GNT1;
Organism Homo sapiens (Human)

PRO ID PR:O43505
DAG View
PRO Name beta-1,4-glucuronyltransferase 1 (human)
Definition A beta-1,4-glucuronyltransferase 1 that is encoded in the genome of human.
Short Label hB4GAT1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43505 (B4GAT1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K60 Ubiquitination PhosphoSitePlus
T65 Phosphorylation PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
N204 N-Glycosylation GlyGen 23090970, 24190977
N300 N-Glycosylation GlyGen 29741879
K377 Ubiquitination PhosphoSitePlus
K386 Ubiquitination PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
S411 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T65 A65 Biomuta DOID:263 / kidney cancer [ cosmic ]
S69 F69 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
K188 E188 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K394 N394 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ] DOID:3571 / liver cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ]