Protein Information

Cytoscape View


UniProt AC / UniProt ID O43490 / PROM1_HUMAN
Protein Name Prominin-1 precursor
Gene Name Name: PROM1
Synonyms:PROML1;ORFNames:MSTP061;
Organism Homo sapiens (Human)

PRO ID PR:O43490
DAG View
PRO Name prominin-1 (human)
Definition A prominin-1 that is encoded in the genome of human.
Short Label hPROM1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43490 (PROM1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y34 Phosphorylation PhosphoSitePlus
K82 Acetylation PhosphoSitePlus
Y219 Phosphorylation PhosphoSitePlus
K225 Acetylation UniProt 24556617
K257 Acetylation UniProt 24556617
K264 Acetylation UniProt 24556617
T266 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S275 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
T276 Phosphorylation phospho.ELM   PhosphoSitePlus 17081983
S719 Phosphorylation PhosphoSitePlus
S733 Phosphorylation PhosphoSitePlus
T739 Phosphorylation PhosphoSitePlus
S824 Phosphorylation PhosphoSitePlus
Y828 Phosphorylation P12931 (SRC) , P06241 (FYN) PhosphoSitePlus   RLIMS-P   Signor 30783186, 19296573, 26029999, ...23569237, 30328220
T833 Phosphorylation PhosphoSitePlus
Y852 Phosphorylation P12931 (SRC) , P06241 (FYN) PhosphoSitePlus   RLIMS-P   Signor 30783186, 19296573
S863 Phosphorylation PhosphoSitePlus   UniProt 21406692
Site PTM Type PTM Enzyme Score Source PMID
T266 Phosphorylation HPRD 17081983
S275 Phosphorylation HPRD 17081983
T276 Phosphorylation HPRD 17081983
Site PTM Type PTM Enzyme Score Source PMID
Y819 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S824 * Biomuta DOID:3571 / liver cancer [ icgc ]
Y828 * Biomuta DOID:3571 / liver cancer [ icgc ]
Y828 H828 Biomuta DOID:9256 / colorectal cancer [ tcga ]
Y852 C852 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]