Protein Information

Cytoscape View


UniProt AC / UniProt ID O43451 / MGA_HUMAN
Protein Name Maltase-glucoamylase, intestinal
Gene Name Name: MGAM
Synonyms:MGA,MGAML;
Organism Homo sapiens (Human)

PRO ID PR:O43451
DAG View
PRO Name maltase-glucoamylase, intestinal (human)
Definition A maltase-glucoamylase, intestinal that is encoded in the genome of human.
Short Label hMGAM
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43451 (MGAM) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T10 Phosphorylation HPRD   PhosphoSitePlus 20166139
S17 Phosphorylation HPRD   PhosphoSitePlus 20166139
S27 Phosphorylation HPRD   PhosphoSitePlus 20166139
N295 N-Glycosylation UniProt 18036614
Y385 Phosphorylation PhosphoSitePlus
T389 Phosphorylation PhosphoSitePlus
S461 Phosphorylation PhosphoSitePlus
N479 N-Glycosylation UniProt 18036614
S618 Phosphorylation PhosphoSitePlus
Y712 Phosphorylation PhosphoSitePlus
N827 N-Glycosylation UniProt 18036614
Y1172 Phosphorylation PhosphoSitePlus
Y1173 Phosphorylation PhosphoSitePlus
T1290 Phosphorylation PhosphoSitePlus
Y1613 Phosphorylation PhosphoSitePlus
Y1620 Phosphorylation PhosphoSitePlus
T1621 Phosphorylation PhosphoSitePlus
Y1683 Phosphorylation PhosphoSitePlus
Y1685 Phosphorylation PhosphoSitePlus
Y1686 Phosphorylation PhosphoSitePlus
T1687 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
N295 S295 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
T389 I389 Biomuta DOID:11934 / head and neck cancer [ icgc, tcga ]
T389 S389 Biomuta DOID:1324 / lung cancer [ tcga ]
T1621 I1621 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
Y1683 N1683 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y1686 F1686 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
T1687 M1687 Biomuta DOID:1319 / brain cancer [ icgc ] DOID:3070 / malignant glioma [ cosmic ]