Protein Information

Cytoscape View


UniProt AC / UniProt ID O43426 / SYNJ1_HUMAN
Protein Name Synaptojanin-1
Gene Name Name: SYNJ1
Synonyms:KIAA0910;
Organism Homo sapiens (Human)

PRO ID PR:O43426
DAG View
PRO Name synaptojanin-1 (human)
Definition A synaptojanin-1 that is encoded in the genome of human.
Short Label hSYNJ1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43426 (SYNJ1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S4 Phosphorylation PhosphoSitePlus
K5 Ubiquitination PhosphoSitePlus
Y60 Phosphorylation PhosphoSitePlus
S242 Phosphorylation PhosphoSitePlus
S244 Phosphorylation PhosphoSitePlus
S245 Phosphorylation PhosphoSitePlus
R284 Methylation PhosphoSitePlus
S304 Phosphorylation PhosphoSitePlus
K352 Ubiquitination PhosphoSitePlus
T443 Phosphorylation PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
K492 Ubiquitination PhosphoSitePlus
T498 Phosphorylation PhosphoSitePlus
T499 Phosphorylation PhosphoSitePlus
K515 Acetylation PhosphoSitePlus
K518 Acetylation PhosphoSitePlus
K554 Methylation PhosphoSitePlus
K577 Ubiquitination PhosphoSitePlus
T680 Phosphorylation PhosphoSitePlus
S695 Phosphorylation PhosphoSitePlus
K785 Ubiquitination PhosphoSitePlus
K798 Ubiquitination PhosphoSitePlus
S830 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332
S1044 Phosphorylation PhosphoSitePlus
S1045 Phosphorylation PhosphoSitePlus
T1048 Phosphorylation PhosphoSitePlus
S1049 Phosphorylation PhosphoSitePlus
S1053 Phosphorylation PhosphoSitePlus
S1080 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1083 Phosphorylation phospho.ELM 18669648
T1092 Phosphorylation PhosphoSitePlus
S1150 Phosphorylation PhosphoSitePlus
T1166 Phosphorylation PhosphoSitePlus
S1178 Phosphorylation PhosphoSitePlus
Y1191 Phosphorylation PhosphoSitePlus
T1220 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 24275569
S1223 Phosphorylation PhosphoSitePlus
T1230 Phosphorylation PhosphoSitePlus
T1282 Phosphorylation PhosphoSitePlus
S1290 Phosphorylation PhosphoSitePlus
S1292 Phosphorylation PhosphoSitePlus   UniProt 23186163
S1293 Phosphorylation neXtProt   PhosphoSitePlus 22371566
S1295 Phosphorylation PhosphoSitePlus
S1302 Phosphorylation PhosphoSitePlus
S1318 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 20068231
S1341 Phosphorylation PhosphoSitePlus
S1345 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T1349 Phosphorylation PhosphoSitePlus
S1385 Phosphorylation PhosphoSitePlus
S1391 Phosphorylation PhosphoSitePlus
S1392 Phosphorylation PhosphoSitePlus
R1409 Methylation PhosphoSitePlus
S1421 Phosphorylation PhosphoSitePlus
S1439 Phosphorylation PhosphoSitePlus
S1456 Phosphorylation PhosphoSitePlus
S1457 Phosphorylation PhosphoSitePlus
S1529 Phosphorylation PhosphoSitePlus
S1551 Phosphorylation PhosphoSitePlus   UniProt 18669648
S1565 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
Site PTM Type PTM Enzyme Score Source PMID
S1292 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S1134 Phosphorylation PhosphoSitePlus
T1138 Phosphorylation PhosphoSitePlus
S1147 Phosphorylation PhosphoSitePlus
S1276 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y60 H60 Biomuta DOID:1324 / lung cancer [ tcga ]
S245 T245 Biomuta DOID:1324 / lung cancer [ tcga ]
R284 M284 Biomuta DOID:1115 / sarcoma [ tcga ]
T680 I680 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K785 N785 Biomuta DOID:1612 / breast cancer [ cosmic ]
K798 N798 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S1044 F1044 Biomuta DOID:363 / uterine cancer [ tcga ]
S1150 G1150 Biomuta DOID:363 / uterine cancer [ cosmic, tcga ]
T1282 I1282 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S1302 L1302 Biomuta DOID:1909 / melanoma [ tcga ]
S1385 F1385 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S1421 Y1421 Biomuta DOID:3571 / liver cancer [ icgc ]
S1457 * Biomuta DOID:5041 / esophageal cancer [ tcga ]