iPTMnet Report for O43424 (GRID2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43424 / GRID2_HUMAN
Protein Name Glutamate receptor ionotropic, delta-2 precursor
Gene Name Name: GRID2
Synonyms:GLURD2;
Organism Homo sapiens (Human)

PRO ID PR:O43424
DAG View
PRO Name glutamate receptor ionotropic, delta-2 (human)
Definition A glutamate receptor ionotropic, delta-2 that is encoded in the genome of human.
Short Label hGRID2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43424 (GRID2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T238 Phosphorylation PhosphoSitePlus
T525 Phosphorylation PhosphoSitePlus
Y543 Phosphorylation PhosphoSitePlus
S663 Phosphorylation PhosphoSitePlus
S664 Phosphorylation PhosphoSitePlus
R880 Methylation PhosphoSitePlus
T903 Phosphorylation PhosphoSitePlus
T912 Phosphorylation PhosphoSitePlus
R913 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T238 A238 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T525 I525 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S664 Y664 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S664 F664 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T912 K912 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
R913 * Biomuta DOID:1319 / brain cancer [ cosmic ]