iPTMnet Report for O43405 (COCH)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43405 / COCH_HUMAN
Protein Name Cochlin precursor
Gene Name Name: COCH
Synonyms:COCH5B2;ORFNames:UNQ257/PRO294;
Organism Homo sapiens (Human)

PRO ID PR:O43405
DAG View
PRO Name cochlin (human)
Definition A cochlin that is encoded in the genome of human.
Short Label hCOCH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43405 (COCH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
C34 Methylation IEDB 31844290
C54 Methylation IEDB 31844290
N100 N-Glycosylation GlyGen 23090970, 24190977
S120 Phosphorylation PhosphoSitePlus
T122 Phosphorylation PhosphoSitePlus
T124 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T124 Phosphorylation PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
S139 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T140 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T145 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
N221 N-Glycosylation GlyGen 24190977
T257 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
T339 Phosphorylation PhosphoSitePlus
T340 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S120 F120 Biomuta DOID:4159 / skin cancer [ cosmic ]
T124 A124 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S139 P139 Biomuta DOID:1319 / brain cancer [ cosmic ]
T257 M257 Biomuta DOID:9256 / colorectal cancer [ cosmic ]