iPTMnet Report for O43379 (WDR62)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43379 / WDR62_HUMAN
Protein Name WD repeat-containing protein 62
Gene Name Name: WDR62
Synonyms:C19orf14;
Organism Homo sapiens (Human)

PRO ID PR:O43379
DAG View
PRO Name WD repeat-containing protein 62 (human)
Definition A WD repeat-containing protein 62 that is encoded in the genome of human.
Short Label hWDR62
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43379 (WDR62) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330, 22814378
S6 Phosphorylation PhosphoSitePlus
S32 Phosphorylation PhosphoSitePlus
S33 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 15302935
T46 O-Glycosylation GlyGen 30379171
T46 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 21406692, 18669648
S49 O-Glycosylation GlyGen 30379171
S49 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 21406692, ...20068231
T50 O-Glycosylation GlyGen 30379171
T50 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S52 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
T55 Phosphorylation PhosphoSitePlus
K102 Ubiquitination PhosphoSitePlus
K112 Ubiquitination PhosphoSitePlus
S113 Phosphorylation PhosphoSitePlus
S120 Phosphorylation PhosphoSitePlus
K145 Ubiquitination PhosphoSitePlus
Y156 Phosphorylation PhosphoSitePlus
S164 Phosphorylation PhosphoSitePlus
S399 Phosphorylation IEDB 35494241
S445 Phosphorylation PhosphoSitePlus
K452 Ubiquitination PhosphoSitePlus
K492 Ubiquitination PhosphoSitePlus
S501 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 20068231
K568 Ubiquitination PhosphoSitePlus
K587 Ubiquitination PhosphoSitePlus
S598 Phosphorylation PhosphoSitePlus
K603 Ubiquitination PhosphoSitePlus
S614 Phosphorylation PhosphoSitePlus
K661 Ubiquitination PhosphoSitePlus
Y666 Phosphorylation PhosphoSitePlus
K667 Ubiquitination PhosphoSitePlus
K678 Ubiquitination PhosphoSitePlus
S684 Phosphorylation IEDB   PhosphoSitePlus 32387766
T814 Phosphorylation PhosphoSitePlus
K817 Ubiquitination PhosphoSitePlus
S819 Phosphorylation PhosphoSitePlus
T829 Phosphorylation PhosphoSitePlus
K832 Ubiquitination PhosphoSitePlus
K838 Ubiquitination PhosphoSitePlus
K855 Ubiquitination PhosphoSitePlus
S857 Phosphorylation PhosphoSitePlus
S897 Phosphorylation PhosphoSitePlus   RLIMS-P 28973348
K961 Ubiquitination PhosphoSitePlus
S974 Phosphorylation PhosphoSitePlus
Y975 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S982 Phosphorylation PhosphoSitePlus
S1047 Phosphorylation PhosphoSitePlus
S1048 Phosphorylation PhosphoSitePlus
S1049 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T1053 Phosphorylation P45983 (MAPK8) phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 18669648, 30566428, 25501809, ...16565220
S1070 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16565220, 23186163, 18220336
S1093 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 20068231, 16565220
S1101 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 20068231, 16565220
K1122 Ubiquitination PhosphoSitePlus
S1123 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K1127 Ubiquitination PhosphoSitePlus
R1131 Methylation PhosphoSitePlus
S1134 Phosphorylation PhosphoSitePlus
T1140 Phosphorylation PhosphoSitePlus
Y1142 Phosphorylation PhosphoSitePlus
S1144 Phosphorylation PhosphoSitePlus   UniProt 23186163
C1169 Methylation IEDB 31844290
T1191 Phosphorylation PhosphoSitePlus
T1193 Phosphorylation PhosphoSitePlus
S1194 Phosphorylation PhosphoSitePlus
T1197 Phosphorylation PhosphoSitePlus
S1208 Phosphorylation PhosphoSitePlus
S1219 Phosphorylation IEDB   PhosphoSitePlus 27869121
S1224 Phosphorylation PhosphoSitePlus
S1226 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S1228 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 16565220
S1232 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
T1239 Phosphorylation PhosphoSitePlus
S1248 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 19690332, 18220336
S1249 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332, 18220336
S1255 Phosphorylation PhosphoSitePlus
T1264 Phosphorylation PhosphoSitePlus
T1268 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S1325 Phosphorylation PhosphoSitePlus
S1342 Phosphorylation PhosphoSitePlus
S1348 Phosphorylation PhosphoSitePlus
S1356 Phosphorylation PhosphoSitePlus
S1388 Phosphorylation PhosphoSitePlus
S1405 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935, 16565220
Y1430 Phosphorylation IEDB 35494241
S1436 Phosphorylation PhosphoSitePlus
T1441 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation HPRD 19007248, 19691289
Y9 Phosphorylation HPRD 19007248, 20068231
S33 Phosphorylation HPRD 19413330, 15302935, 19664994, ...19691289, 19664995, 19007248
T46 Phosphorylation HPRD 18669648, 19691289, 20068231
S49 Phosphorylation HPRD 19651622, 18669648, 19007248, ...20068231, 19691289
T50 Phosphorylation HPRD 19651622, 18669648, 19691289, ...20068231
S52 Phosphorylation HPRD 18669648, 19007248, 20068231, ...19691289
Y156 Phosphorylation HPRD 20068231
S164 Phosphorylation HPRD 20068231
S501 Phosphorylation HPRD 18669648, 19007248, 20068231, ...19691289
S614 Phosphorylation HPRD 19691289
T814 Phosphorylation HPRD 19691289
S819 Phosphorylation HPRD 19007248, 19691289
S974 Phosphorylation HPRD 19007248, 19691289
Y975 Phosphorylation HPRD 18669648
S987 Phosphorylation HPRD 17081983
S992 Phosphorylation HPRD 17081983
S995 Phosphorylation HPRD 17081983
S1049 Phosphorylation HPRD 18669648
T1053 Phosphorylation HPRD 18669648, 16565220
S1070 Phosphorylation HPRD 16565220
S1093 Phosphorylation HPRD 20068231, 16565220
S1101 Phosphorylation HPRD 19007248, 20068231, 16565220
S1123 Phosphorylation HPRD 18669648, 19007248, 19691289
T1140 Phosphorylation HPRD 19651622, 20068231
S1144 Phosphorylation HPRD 18707149, 19691289, 19007248
T1191 Phosphorylation HPRD 19007248
S1226 Phosphorylation HPRD 18669648, 20068231
S1228 Phosphorylation HPRD 19413330, 16565220, 18669648, ...18707149, 19415658, 20068231
S1232 Phosphorylation HPRD 18669648
S1249 Phosphorylation HPRD 18669648
T1268 Phosphorylation HPRD 18669648
S1342 Phosphorylation HPRD 20068231
S1348 Phosphorylation HPRD 17081983, 20068231, 19691289
S1405 Phosphorylation HPRD 16565220
S1435 Phosphorylation HPRD 19691289
S1436 Phosphorylation HPRD 19007248, 19691289
T1441 Phosphorylation HPRD 19007248, 19691289
Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation HPRD 19007248, 19691289
Y9 Phosphorylation HPRD 19007248, 20068231
S33 Phosphorylation HPRD 19413330, 19664995, 19664994, ...19691289, 19007248
T46 Phosphorylation HPRD 18669648, 19691289, 20068231
S49 Phosphorylation HPRD 19651622, 18669648, 19007248, ...20068231, 19691289
T50 Phosphorylation HPRD 19651622, 18669648, 19691289, ...20068231
S52 Phosphorylation HPRD 18669648, 19007248, 20068231, ...19691289
Y156 Phosphorylation HPRD 20068231
S164 Phosphorylation HPRD 20068231
S501 Phosphorylation HPRD 18669648, 19007248, 20068231, ...19691289
S614 Phosphorylation HPRD 19691289
T814 Phosphorylation HPRD 19691289
S819 Phosphorylation HPRD 19007248, 19691289
S974 Phosphorylation HPRD 19007248, 19691289
Y975 Phosphorylation HPRD 18669648
S987 Phosphorylation HPRD 17081983
S992 Phosphorylation HPRD 17081983
S995 Phosphorylation HPRD 17081983
S1049 Phosphorylation HPRD 18669648
T1053 Phosphorylation HPRD 18669648
S1070 Phosphorylation HPRD   PhosphoSitePlus 17081983
S1098 Phosphorylation HPRD 20068231
S1106 Phosphorylation HPRD 19007248, 20068231
S1128 Phosphorylation HPRD 18669648, 19007248, 19691289
T1145 Phosphorylation HPRD 19651622, 20068231
S1149 Phosphorylation HPRD 18707149, 19691289, 19007248
T1196 Phosphorylation HPRD 19007248
S1231 Phosphorylation HPRD 18669648, 20068231
S1233 Phosphorylation HPRD 19413330, 18669648, 19415658, ...20068231, 18707149
S1237 Phosphorylation HPRD 18669648
S1254 Phosphorylation HPRD 18669648
T1273 Phosphorylation HPRD 18669648
S1347 Phosphorylation HPRD 20068231
S1353 Phosphorylation HPRD 17081983, 20068231, 19691289
S1440 Phosphorylation HPRD 19691289
S1441 Phosphorylation HPRD 19007248, 19691289
T1446 Phosphorylation HPRD 19007248, 19691289


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S33 Y33 Biomuta DOID:4159 / skin cancer [ cosmic ]
K145 N145 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y156 H156 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K452 I452 Biomuta DOID:1319 / brain cancer [ cosmic, icgc ]
S501 N501 Biomuta DOID:4159 / skin cancer [ cosmic ]
K603 N603 Biomuta DOID:1324 / lung cancer [ cosmic ]
K838 T838 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K855 N855 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S987 N987 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S995 * Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]
S1049 F1049 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
R1131 * Biomuta DOID:363 / uterine cancer [ cosmic ]
S1144 F1144 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S1149 F1149 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T1191 M1191 Biomuta DOID:9256 / colorectal cancer [ icgc ]
T1196 M1196 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S1228 F1228 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1228 Y1228 Biomuta DOID:10534 / stomach cancer [ icgc ]
S1232 N1232 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1233 F1233 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1233 Y1233 Biomuta DOID:10534 / stomach cancer [ icgc ]
S1237 N1237 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1248 P1248 Biomuta DOID:263 / kidney cancer [ cosmic ]
S1248 L1248 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic, icgc ]
S1348 F1348 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1353 F1353 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1388 N1388 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1405 P1405 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S1435 P1435 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1435 Y1435 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S1440 P1440 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S1440 Y1440 Biomuta DOID:4159 / skin cancer [ cosmic, icgc, cosmic, cosmic ] DOID:363 / uterine cancer [ cosmic, icgc, cosmic, icgc ] DOID:1324 / lung cancer [ cosmic ]