iPTMnet Report for O43347 (MSI1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43347 / MSI1H_HUMAN
Protein Name RNA-binding protein Musashi homolog 1
Gene Name Name: MSI1
Organism Homo sapiens (Human)

PRO ID PR:O43347
DAG View
PRO Name RNA-binding protein Musashi homolog 1 (human)
Definition An RNA-binding protein Musashi homolog 1 that is encoded in the genome of human.
Short Label hMSI1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43347 (MSI1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330, 21406692
S12 Phosphorylation HPRD   PhosphoSitePlus 19413330
S15 Phosphorylation PhosphoSitePlus
K58 Ubiquitination PhosphoSitePlus
K76 Ubiquitination PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
K93 Ubiquitination PhosphoSitePlus
K103 Ubiquitination PhosphoSitePlus
S117 O-Glycosylation GlyGen 34105348
K144 Ubiquitination PhosphoSitePlus
S191 Phosphorylation HPRD   PhosphoSitePlus   UniProt 21406692, 19664995
T193 O-Glycosylation GlyGen 35138101, 29237092, 34105348
S195 O-Glycosylation GlyGen 35138101, 29237092, 34105348
R197 Methylation PhosphoSitePlus
R199 Methylation PhosphoSitePlus
R201 Methylation PhosphoSitePlus
T251 Phosphorylation PhosphoSitePlus
S255 Phosphorylation PhosphoSitePlus
S312 Phosphorylation PhosphoSitePlus
S337 Phosphorylation RLIMS-P 25888190


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S117 L117 Biomuta DOID:363 / uterine cancer [ icgc ]
T193 M193 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T251 N251 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T251 A251 Biomuta DOID:1612 / breast cancer [ cosmic ]
S255 R255 Biomuta DOID:3571 / liver cancer [ cosmic ]