iPTMnet Report for O43324 (EEF1E1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43324 / MCA3_HUMAN
Protein Name Eukaryotic translation elongation factor 1 epsilon-1
Gene Name Name: EEF1E1
Synonyms:AIMP3,P18;
Organism Homo sapiens (Human)

PRO ID PR:O43324
DAG View
PRO Name eukaryotic translation elongation factor 1 epsilon-1 (human)
Definition A eukaryotic translation elongation factor 1 epsilon-1 that is encoded in the genome of human.
Short Label hEEF1E1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43324 (EEF1E1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 O-Glycosylation GlyGen 33214551, 34019948, 33465208, ...35254053
S8 Phosphorylation PhosphoSitePlus
K12 Acetylation PhosphoSitePlus
K12 Ubiquitination PhosphoSitePlus
S13 Phosphorylation PhosphoSitePlus
K18 Ubiquitination PhosphoSitePlus
K21 Acetylation PhosphoSitePlus
Y22 Phosphorylation PhosphoSitePlus
S23 Phosphorylation PhosphoSitePlus
K53 Ubiquitination PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
Y59 Phosphorylation PhosphoSitePlus
K68 Ubiquitination PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
Y101 Phosphorylation PhosphoSitePlus
T132 O-Glycosylation GlyGen 33214551, 34019948, 33465208, ...35254053
K138 Acetylation PhosphoSitePlus   UniProt 19608861
K166 Acetylation PhosphoSitePlus
R168 Methylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K12 R12 Biomuta DOID:1324 / lung cancer [ cosmic ]
K21 T21 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K88 R88 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]