iPTMnet Report for O43312 (MTSS1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID O43312 / MTSS1_HUMAN
Protein Name Protein MTSS 1
Gene Name Name: MTSS1
Synonyms:KIAA0429,MIM;
Organism Homo sapiens (Human)

PRO ID PR:O43312
DAG View
PRO Name protein MTSS 1 (human)
Definition A protein MTSS 1 that is encoded in the genome of human.
Short Label hMTSS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O43312 (MTSS1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T144 Phosphorylation PhosphoSitePlus
K146 Acetylation PhosphoSitePlus
K149 Acetylation PhosphoSitePlus
K150 Acetylation PhosphoSitePlus
T258 Phosphorylation phospho.ELM   PhosphoSitePlus 18088087
S261 Phosphorylation phospho.ELM   PhosphoSitePlus 18088087
S262 Phosphorylation PhosphoSitePlus
T265 Phosphorylation PhosphoSitePlus
T266 Phosphorylation PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
S275 Phosphorylation PhosphoSitePlus
S276 Phosphorylation PhosphoSitePlus
S294 Phosphorylation PhosphoSitePlus
S318 Phosphorylation PhosphoSitePlus
S322 Phosphorylation PhosphoSitePlus   RLIMS-P 29175021, 24318128
S322 Phosphorylation P48730 (CSNK1D) PhosphoSitePlus 24318128
S326 Phosphorylation RLIMS-P 30858428
Y390 Phosphorylation PhosphoSitePlus
Y393 Phosphorylation PhosphoSitePlus
Y394 Phosphorylation PhosphoSitePlus
Y418 Phosphorylation PhosphoSitePlus
T425 Phosphorylation PhosphoSitePlus
S460 Phosphorylation PhosphoSitePlus
S545 O-Glycosylation GlyGen 30379171
S546 O-Glycosylation GlyGen 30379171
T547 O-Glycosylation GlyGen 30379171
S557 Phosphorylation PhosphoSitePlus
S569 Phosphorylation PhosphoSitePlus
T576 O-Glycosylation GlyGen 32938750
T588 Phosphorylation PhosphoSitePlus
S594 Phosphorylation PhosphoSitePlus
T595 Phosphorylation PhosphoSitePlus
K596 Acetylation PhosphoSitePlus
S598 Phosphorylation PhosphoSitePlus
T603 Phosphorylation PhosphoSitePlus
T613 Phosphorylation PhosphoSitePlus
S644 Phosphorylation PhosphoSitePlus
S649 Phosphorylation PhosphoSitePlus
S693 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T258 Phosphorylation HPRD 18088087
S261 Phosphorylation HPRD 18088087
S644 Phosphorylation HPRD 20058876
S649 Phosphorylation HPRD 20058876


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation O43312 (MTSS1) S322 Q9Y297 (BTRC) unknown eFIP 24318128


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T144 S144 Biomuta DOID:1324 / lung cancer [ cosmic ]
T258 M258 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:10283 / prostate cancer [ cosmic ]
S294 F294 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S326 F326 Biomuta DOID:4159 / skin cancer [ cosmic ]
Y390 F390 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
S644 C644 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]