Protein Information

Cytoscape View

UniProt AC / UniProt ID O43306 / ADCY6_HUMAN
Protein Name Adenylate cyclase type 6
Gene Name Name: ADCY6
Organism Homo sapiens (Human)

PRO ID PR:O43306
DAG View
PRO Name adenylate cyclase type 6 (human)
Definition An adenylate cyclase type 6 that is encoded in the genome of human.
Short Label hADCY6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O43306 (ADCY6) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
K16 Ubiquitination PhosphoSitePlus
T40 Phosphorylation PhosphoSitePlus
S54 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18088087, 15302935, 23186163
K80 Ubiquitination PhosphoSitePlus
K129 Ubiquitination PhosphoSitePlus
S207 Phosphorylation PhosphoSitePlus
S212 Phosphorylation PhosphoSitePlus
S477 Phosphorylation PhosphoSitePlus
K568 Ubiquitination PhosphoSitePlus
T572 Phosphorylation PhosphoSitePlus
S576 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18669648, 18088087
S607 Phosphorylation PhosphoSitePlus
S608 Phosphorylation PhosphoSitePlus
S732 Phosphorylation neXtProt 11327830
S732 Phosphorylation P04049 (RAF1) neXtProt 11327830
S734 Phosphorylation neXtProt 11327830
S734 Phosphorylation P04049 (RAF1) neXtProt 11327830
S738 Phosphorylation neXtProt 11327830
S738 Phosphorylation P04049 (RAF1) neXtProt 11327830
S742 Phosphorylation neXtProt 11327830
S742 Phosphorylation P04049 (RAF1) neXtProt 11327830
K934 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S54 Phosphorylation HPRD 19413330, 15302935, 18578522, ...18088087
S576 Phosphorylation HPRD 18669648, 18088087

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K568 R568 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S738 L738 Biomuta DOID:1324 / lung cancer [ tcga ]